Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 20/20 | 0.78 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.59 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5643183 | 0.87 | F10 (0.77) | F10KLKB1KCNH2 | |
| SCHEMBL5643620 | 0.86 | F10 (0.76) | F10KLKB1KCNH2 | |
| SCHEMBL5643563 | 0.85 | F10 (0.75) | F10KCNH2 | |
| SCHEMBL5642495 | 0.84 | F10 (0.75) | F10KCNH2 | |
| SCHEMBL5642675 | 0.82 | F10 (0.77) | F10KCNH2 | |
| SCHEMBL5645469 | 0.82 | F10 (0.57) | F10KLKB1KCNH2 | |
| SCHEMBL5643550 | 0.81 | F10 (0.72) | F10KCNH2 | |
| SCHEMBL5646551 | 0.81 | F10 (0.67) | F10KLKB1KCNH2 | |
| SCHEMBL5643311 | 0.81 | F10 (0.71) | F10KLKB1KCNH2 | |
| SCHEMBL5644532 | 0.80 | F10 (0.60) | F10KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7312214-B2 | 1, 1-disubstituted cycloalkyl derivatives as factor Xa inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2007-12-25 | — | — | US | disclosed |