Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 20/20 | 0.77 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.59 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5643620 | 0.97 | F10 (0.76) | F10KCNH2KLKB1 | |
| SCHEMBL5642450 | 0.92 | F10 (0.75) | F10KCNH2KLKB1 | |
| SCHEMBL5644177 | 0.89 | F10 (0.65) | F10KLKB1 | |
| SCHEMBL5643563 | 0.87 | F10 (0.75) | F10KCNH2 | |
| SCHEMBL5645840 | 0.87 | F10 (0.78) | F10KCNH2KLKB1 | |
| SCHEMBL5642495 | 0.86 | F10 (0.75) | F10KCNH2 | |
| SCHEMBL5643992 | 0.86 | F10 (0.66) | F10 | |
| SCHEMBL5642343 | 0.86 | F10 (0.66) | F10KCNH2 | |
| SCHEMBL5644869 | 0.84 | F10 (0.63) | F10KCNH2 | |
| SCHEMBL5642525 | 0.84 | F10 (0.67) | F10KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040254158-A1 | Anticoagulants; atherosclerosis; strokes; thrombosis; cardiovascular disorders | BRISTOL-MYERS SQUIBB COMPANY | 2004-12-16 | — | — | US | claimed |
| US-7312214-B2 | 1, 1-disubstituted cycloalkyl derivatives as factor Xa inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2007-12-25 | — | — | US | disclosed |
| US-20040254158-A1 | Anticoagulants; atherosclerosis; strokes; thrombosis; cardiovascular disorders | BRISTOL-MYERS SQUIBB COMPANY | 2004-12-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040254158-A1 | Anticoagulants; atherosclerosis; strokes; thrombosis; cardiovascular disorders | SERPINC1, PCSK9, PLAT | F10 14/4885KCNH2 991/4885KLKB1 429/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.