Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | IDH1 | O75874 | 3/20 | 0.42 |
| ▸ | IDH2 | P48735 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.41 |
| ▸ | SDHB | P21912 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | STAT3 | P40763 | 1/20 | 0.41 |
| ▸ | STAT1 | P42224 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3381636 | 0.84 | MEN1 (0.60) | MEN1KMT2ARAB9AASIC3HSD17B10 | |
| SCHEMBL7814795 | 0.84 | MEN1 (0.60) | MEN1KMT2ARAB9AASIC3HSD17B10 | |
| SCHEMBL11931991 | 0.84 | MEN1 (0.60) | MEN1KMT2ARAB9AASIC3HSD17B10 | |
| SCHEMBL1960761 | 0.84 | MEN1 (0.60) | MEN1KMT2ARAB9AASIC3HSD17B10 | |
| SCHEMBL10056535 | 0.79 | MEN1 (0.65) | MEN1KMT2ARAB9AASIC3HSD17B10 | |
| SCHEMBL14198199 | 0.77 | MEN1 (0.50) | MEN1KMT2ARAB9AASIC3HSD17B10 | |
| SCHEMBL25885404 | 0.76 | MEN1 (0.54) | MEN1KMT2ARAB9AASIC3HSD17B10 | |
| SCHEMBL23746886 | 0.74 | MEN1 (0.47) | MEN1KMT2ARAB9AASIC3HSD17B10 | |
| SCHEMBL15469175 | 0.74 | MEN1 (0.47) | MEN1KMT2ARAB9AASIC3KDM4E | |
| SCHEMBL58442 | 0.73 | MEN1 (1.00) | MEN1KMT2ARAB9AASIC3HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9029539-B2 | Metal complexes with bipodal ligands | MERCK PATENT GMBH (DE) | 2015-05-12 | — | — | US | disclosed |
| US-9029539-B2 | Metal complexes with bipodal ligands | MERCK PATENT GMBH (DE) | 2015-05-12 | — | — | US | disclosed |
| US-9029539-B2 | Metal complexes with bipodal ligands | MERCK PATENT GMBH (DE) | 2015-05-12 | — | — | US | disclosed |
| EP-1678190-B1 | METAL COMPLEXES WITH BIPODAL LIGANDS | MERCK PATENT GMBH (DE) | 2012-11-21 | — | — | EP | disclosed |
| EP-1678190-B1 | METAL COMPLEXES WITH BIPODAL LIGANDS | MERCK PATENT GMBH (DE) | 2012-11-21 | — | — | EP | disclosed |
| US-20070082284-A1 | Metal complexes with bipodal ligands | MERCK PATENT GMBH (DE) | 2007-04-12 | — | — | US | disclosed |
| US-20070082284-A1 | Metal complexes with bipodal ligands | MERCK PATENT GMBH (DE) | 2007-04-12 | — | — | US | disclosed |
| US-20070082284-A1 | Metal complexes with bipodal ligands | MERCK PATENT GMBH (DE) | 2007-04-12 | — | — | US | disclosed |
| EP-1678190-A1 | METAL COMPLEXES WITH BIPODAL LIGANDS | Merck Patent GmbH (DE) | 2006-07-12 | — | — | EP | disclosed |
| WO-2005042550-A1 | METAL COMPLEXES WITH BIPODAL LIGANDS | MERCK PATENT GMBH (DE) | 2005-05-12 | — | — | WO | disclosed |