SCHEMBL5646377

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1082631	0.93	HIF1A (1.00)	HIF1ALMNACYP1A2CYP2D6CYP2C9
	Hydrochloric Acid SCHEMBL8646699	0.92	HIF1A (0.98)	HIF1ALMNACYP1A2CYP2D6CYP2C9
	SCHEMBL8645594	0.92	AKR1C3 (1.00)	HIF1ALMNACYP1A2CYP2D6CYP2C9
	Indomethacin SCHEMBL27521872	0.91	PTGS2 (0.92)	HIF1ALMNACYP1A2CYP2D6CYP2C9
	SCHEMBL2600801	0.90	AKR1C3 (1.00)	HIF1ALMNACYP1A2CYP2D6CYP2C9
	Indomethacin SCHEMBL28072579	0.89	PTGS2 (0.98)	HIF1ALMNACYP1A2CYP2D6CYP2C9
	SCHEMBL12747878	0.89	AKR1C3 (0.89)	HIF1ALMNACYP1A2CYP2D6CYP2C9
	Iodoindomethacin SCHEMBL13290295	0.88	AKR1C3 (0.87)	HIF1ALMNACYP1A2CYP2D6CYP2C9
	SCHEMBL5796934	0.88	AKR1C3 (1.00)	HIF1ALMNACYP1A2CYP2D6CYP2C9
	Indomethacin SCHEMBL3518614	0.88	PTGS2 (1.00)	HIF1ALMNACYP1A2CYP2D6CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.