SCHEMBL5647622

SCHEMBL5647622

CCCCCC[SiH](O[Si](C)(C)C)O[Si](C)(C)C

nearest known ligand 0.38

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TSHR P16473 6/20 0.38
THRB P10828 1/20 0.38
LMNA P02545 3/20 0.31
DNM1 Q05193 5/20 0.31
ALDH1A1 P00352 4/20 0.31
MEN1 O00255 2/20 0.31
KMT2A Q03164 2/20 0.31
HSD17B10 Q99714 1/20 0.31
SLC22A1 O15245 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19170420 1.00 TSHR (0.38) TSHRTHRBLMNADNM1ALDH1A1
SCHEMBL21112851 0.98 TSHR (0.33) TSHRTHRBALDH1A1
SCHEMBL5653079 0.90 LMNA (0.30) TSHRLMNA
SCHEMBL17088171 0.84 LMNA (0.30) LMNA
SCHEMBL21112543 0.83 TSHR (0.32) TSHRTHRBLMNA
SCHEMBL19926979 0.81 TSHR (0.38) TSHRTHRBLMNADNM1ALDH1A1
SCHEMBL21112976 0.80
SCHEMBL3081364 0.79
SCHEMBL16487400 0.79 TSHR (0.36) TSHRTHRBLMNA
SCHEMBL16487403 0.79 TSHR (0.36) TSHRTHRBLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3507104-B1 PRODUCTION OF CIS-1,4-POLYDIENES WITH MULTIPLE SILANE FUNCTIONAL GROUPS PREPARED BYIN-SITU BRIDGESTONE CORP (JP) 2024-03-27 EP disclosed
US-10975178-B2 Production of cis-1,4-polydienes with multiple silane functional groups prepared by in-situ hydrosilylation of polymer cement BRIDGESTONE CORPORATION (JP) 2021-04-13 US disclosed
US-20190211120-A1 Production Of Cis-1,4-Polydienes With Multiple Silane Functional Groups Prepared By In-Situ Hydrosilylation Of Polymer Cement BRIDGESTONE CORPORATION (JP) 2019-07-11 US disclosed
US-7211543-B2 Photocatalyst composition ASAHI KASEI KABUSHIKI KAISHA (JP) 2007-05-01 US disclosed
US-20050227859-A1 Photocatalyst composition ASAHI KASEI KABUSHIKI KAISHA (JP) 2005-10-13 US disclosed
EP-1518601-A1 PHOTOCATALYST COMPOSITION Asahi Kasei Kabushiki Kaisha (JP) 2005-03-30 EP disclosed