SCHEMBL5648710

SCHEMBL5648710

COc1ccc(C=C(C(=O)OC2CC(C)(C)NC(C)(C)C2)C(=O)OC2CC(C)(C)NC(C)(C)C2)cc1

nearest known ligand 0.55

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.46
ATM Q13315 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
KDM4E B2RXH2 2/20 0.38
ALDH1A1 P00352 2/20 0.38
MAPT P10636 1/20 0.38
HPGD P15428 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
F3 P13726 1/20 0.37
EZH2 Q15910 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13148368 0.86 ALDH1A1 (0.40) GAAKDM4EALDH1A1MAPTHPGD
SCHEMBL78186 0.84 HTT (0.40) GAAKDM4EALDH1A1MAPTHPGD
SCHEMBL14007425 0.83 GAA (0.41) GAAATML3MBTL1KDM4EALDH1A1
SCHEMBL13433229 0.83 GAA (0.41) GAAATML3MBTL1KDM4EALDH1A1
SCHEMBL10079245 0.82 GAA (0.39) GAAATML3MBTL1KDM4EALDH1A1
SCHEMBL24453525 0.81 HTT (0.38) GAAKDM4EALDH1A1MAPTHPGD
SCHEMBL9207163 0.81 HTT (0.55) GAAATMALDH1A1MAPTF3
SCHEMBL9207159 0.81 HTT (0.55) GAAATMALDH1A1MAPTF3
SCHEMBL14001979 0.79 ALDH1A1 (0.38) GAAKDM4EALDH1A1MAPTHPGD
SCHEMBL8098334 0.79 GAA (0.30) GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6992124-B2 Polyolefin molding compound for producing calendered films/sheets CLARIANT GMBH (DE) 2006-01-31 US claimed
EP-0934972-B1 Polyolefin moulding matters for manufacture of calandered foils/boards CLARIANT GMBH (DE) 2004-04-28 EP claimed
US-20020006992-A1 POLYOLEFIN MOLDING COMPOUND FOR PRODUCING CALENDERED FILMS/SHEETS CLARIANT PRODUKTE (DEUTSCHLAND) GMBH (DE) 2002-01-17 US claimed
EP-0934972-A2 Polyolefin moulding matters for manufacture of calandered foils/boards Clariant GmbH (DE) 1999-08-11 EP claimed
US-9388338-B2 Liquid crystal mixture MERCK PATENT GMBH (DE) 2016-07-12 US disclosed
US-9388338-B2 Liquid crystal mixture MERCK PATENT GMBH (DE) 2016-07-12 US disclosed
US-8053169-B2 an N-vinylcaptrolactam; a polymerization initiator; and organic amine compounds as light stabilizers; curing FUJIFILM CORPORATION (JP) 2011-11-08 US disclosed
US-20080074480-A1 INK COMPOSITION, INKJET RECORDING METHOD, AND PRINTED MATERIAL FUJIFILM CORPORATION (JP) 2008-03-27 US disclosed
US-20080063981-A1 Ink composition, inkjet recording method, printed material, and process for producing lithographic printing plate FUJIFILM CORPORATION (JP) 2008-03-13 US disclosed
US-7297734-B2 Process for preparing synergistic stabilizer mixtures CLARIANT PRODUKTE (DEUTSCHLAND) GMBH (DE) 2007-11-20 US disclosed
EP-1474471-B8 PROCESS FOR PREPARING A SYNERGISTIC STABILIZER MIXTURE CLARIANT PRODUKTE DEUTSCHLAND (DE) 2006-10-04 EP disclosed
US-7105590-B2 Phenolfree stabilization of polyolefins CLARIANT FINANCE (BVI) LIMITED (VG) 2006-09-12 US disclosed
WO-2000077084-A1 STABILIZATION OF PLASTICS AND ARTICLES PRODUCED OR COATED THEREWITH CLARIANT FINANCE (BVI) LIMITED (VG) 2000-12-21 WO disclosed
EP-0934972-A2 Polyolefin moulding matters for manufacture of calandered foils/boards Clariant GmbH (DE) 1999-08-11 EP disclosed
EP-0690060-B1 Polyalkylpiperidine compounds CLARIANT GMBH (DE) 1998-09-09 EP disclosed
US-5633378-A STABILIZER FOR POLYMERS HOECHST AKTIENGESELLSCHAFT (DE) 1997-05-27 US disclosed
EP-0742254-A2 Resin having reduced rate of sulfur acceptance HOECHST AKTIENGESELLSCHAFT (DE) 1996-11-13 EP disclosed
EP-0718357-A2 Flame-resistant moulding composition having improved light stability HOECHST AKTIENGESELLSCHAFT (DE) 1996-06-26 EP disclosed
EP-0705836-A1 Polyalkylpiperidine compounds HOECHST AKTIENGESELLSCHAFT (DE) 1996-04-10 EP disclosed
EP-0690060-A1 Two crystal modifications of a diketopyrrolopyrrole HOECHST AKTIENGESELLSCHAFT (DE) 1996-01-03 EP disclosed