Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA4 | P22748 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.45 |
| ▸ | MC4R | P32245 | 2/20 | 0.45 |
| ▸ | MC5R | P33032 | 2/20 | 0.45 |
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
| ▸ | MC3R | P41968 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SLC13A5 | Q86YT5 | 1/20 | 0.41 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1999150 | 0.81 | MC5R (0.51) | CYP1A2CYP2A6CA12CA1CA2 | |
| SCHEMBL349780 | 0.77 | ALDH1A1 (0.52) | CYP1A2CA12CA1CA2SIGMAR1 | |
| SCHEMBL29560700 | 0.76 | CYP1A2 (0.65) | CYP1A2CYP2A6HDAC1HDAC8SIGMAR1 | |
| SCHEMBL6240981 | 0.76 | CYP1A2 (0.65) | CYP1A2CYP2A6HDAC1HDAC8SIGMAR1 | |
| SCHEMBL835672 | 0.76 | CYP1A2 (0.51) | CYP1A2CYP2A6HDAC1HDAC8SIGMAR1 | |
| SCHEMBL2255106 | 0.76 | HDAC1 (0.53) | CYP1A2CYP2A6CA12CA1CA2 | |
| SCHEMBL1680520 | 0.76 | TAAR1 (0.57) | CYP1A2CYP2A6SIGMAR1MC4RMC5R | |
| SCHEMBL761211 | 0.75 | CA12 (0.49) | CYP1A2CYP2A6CA12CA1CA2 | |
| SCHEMBL5420659 | 0.74 | FFAR1 (0.48) | HDAC1KMT2A | |
| Hydrochloric Acid SCHEMBL6559137 | 0.74 | TAAR1 (0.55) | CYP1A2CYP2A6SIGMAR1MC4RMC5R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070049620-A1 | Cyclic tertiary amine compound | SANKYO COMPANY, LIMITED (JP) | 2007-03-01 | — | — | US | disclosed |
| EP-1632488-A1 | CYCLIC TERTIARY AMINE COMPOUND | Sankyo Company, Limited (JP) | 2006-03-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070049620-A1 | Cyclic tertiary amine compound | MYD88, IL5, BRD4 | CYP1A2 877/4885CYP2A6 3722/4885CA12 3926/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.