Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.63 |
| ▸ | POLB | P06746 | 2/20 | 0.63 |
| ▸ | GFER | P55789 | 1/20 | 0.63 |
| ▸ | P2RX3 | P56373 | 8/20 | 0.50 |
| ▸ | P2RX2 | Q9UBL9 | 8/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | MGAM | O43451 | 1/20 | 0.41 |
| ▸ | SI | P14410 | 1/20 | 0.41 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29631745 | 0.87 | GAA (0.58) | GAAPOLBGFERP2RX3P2RX2 | |
| SCHEMBL2953510 | 0.86 | GAA (0.59) | GAAPOLBGFERP2RX3P2RX2 | |
| SCHEMBL1099448 | 0.84 | GAA (0.55) | GAAPOLBGFERP2RX3P2RX2 | |
| SCHEMBL16231126 | 0.83 | POLB (0.59) | GAAPOLBGFERP2RX3P2RX2 | |
| SCHEMBL12462023 | 0.82 | GAA (0.49) | GAAPOLBGFERP2RX3P2RX2 | |
| SCHEMBL13124768 | 0.82 | NPC1 (0.62) | GAAPOLBGFERP2RX3P2RX2 | |
| SCHEMBL14200081 | 0.81 | GAA (0.57) | GAAPOLBGFERP2RX3P2RX2 | |
| SCHEMBL926329 | 0.81 | L3MBTL1 (0.67) | GAAPOLBL3MBTL1PKMALDH1A1 | |
| SCHEMBL26551436 | 0.79 | POLB (0.96) | GAAPOLBGFERP2RX3P2RX2 | |
| SCHEMBL12889915 | 0.79 | GAA (0.57) | GAAPOLBGFERP2RX3P2RX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9791399-B2 | Derivatization of carbon | SCHLUMBERGER TECHNOLOGY CORPORATION (US) | 2017-10-17 | — | — | US | disclosed |
| US-20070299092-A1 | Quinone Substituted Quinazoline and Quinoline Kinase Inhibitors | WYETH (US) | 2007-12-27 | — | — | US | disclosed |
| WO-2005115145-A2 | QUINONE SUBSTITUTED QUINAZOLINE AND QUINOLINE KINASE INHIBITORS | WYETH (US) | 2005-12-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070299092-A1 | Quinone Substituted Quinazoline and Quinoline Kinase Inhibitors | KDR, FLT1, FLT4 | GAA 2151/4885POLB 1514/4885GFER 2880/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.