Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | PDE5A | O76074 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | UBE2N | P61088 | 1/20 | 0.46 |
| ▸ | NAMPT | P43490 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5653271 | 0.93 | CYP2D6 (0.61) | CYP2D6CYP2C9TSHRHSD17B10SMN1; SMN2 | |
| SCHEMBL5647370 | 0.89 | POLB (0.51) | CYP2D6CYP2C9TSHRUSP2HTT | |
| SCHEMBL5649561 | 0.88 | TSHR (0.52) | CYP2D6CYP2C9TSHRUSP2HTT | |
| SCHEMBL5649790 | 0.88 | CYP2D6 (0.52) | CYP2D6CYP2C9TSHRUSP2HTT | |
| SCHEMBL5651583 | 0.87 | SMN1; SMN2 (0.50) | CYP2D6CYP2C9TSHRSMN1; SMN2ALDH1A1 | |
| SCHEMBL5653250 | 0.86 | TSHR (0.55) | CYP2D6CYP2C9TSHRUSP2HTT | |
| SCHEMBL5651323 | 0.84 | TSHR (0.53) | CYP2D6CYP2C9TSHRUSP2HTT | |
| SCHEMBL5651548 | 0.84 | PDE5A (0.54) | HSD17B10PDE5AALDH1A1KDM4EMEN1 | |
| SCHEMBL5650259 | 0.83 | MEN1 (0.57) | CYP2D6CYP2C9TSHRUSP2HTT | |
| SCHEMBL5650235 | 0.83 | CYP2C9 (0.56) | CYP2D6CYP2C9TSHRUSP2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7220769-B2 | Azolylbenzamides and analogues and their use for treating osteoporosis | NIKEM RESEARCH S.R.L. (IT) | 2007-05-22 | — | — | US | disclosed |
| US-20050038095-A1 | Azolylbenzamides and analogues and their use for treating osteoporosis | 3-V BIOSCIENCES, INC. | 2005-02-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050038095-A1 | Azolylbenzamides and analogues and their use for treating osteoporosis | NR0B2, NR0B1, NCOR1 | CYP2D6 3252/4885CYP2C9 3314/4885TSHR 161/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.