SCHEMBL5649245

SCHEMBL5649245

C=C(Cl)CNC=O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1288828 0.74
SCHEMBL11554211 0.74
SCHEMBL1300385 0.72
SCHEMBL5651970 0.72
SCHEMBL15480707 0.72
SCHEMBL8938871 0.72
SCHEMBL13350760 0.67 LMNA (0.32)
SCHEMBL5651520 0.67
SCHEMBL81843 0.65
SCHEMBL24684700 0.65

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113121465-A Synthesis process of 2-chloro-5-chloromethyl thiazole 安徽海顺化工有限公司 2021-07-16 CN disclosed
CN-101250165-A Insecticidal bis-heterocyclic compounds SHANDONG PESTICIDES RES INST (CN) 2008-08-27 CN disclosed
US-20070049620-A1 Cyclic tertiary amine compound SANKYO COMPANY, LIMITED (JP) 2007-03-01 US disclosed
EP-1632488-A1 CYCLIC TERTIARY AMINE COMPOUND Sankyo Company, Limited (JP) 2006-03-08 EP disclosed
EP-0850231-B1 PROCESS FOR PREPARING A 2-CHLORO-5-CHLOROMETHYL-THIAZOLE COMPOUND SYNGENTA PARTICIPATIONS AG (CH) 2003-04-02 EP disclosed
US-6187927-B1 REACTING 2-CHLOROALLYLFORMAMIDE WITH DEHYDRATING, HALOGENATING, AND SULFURIZING AGENTS NOVARTIS CROP PROTECTION, INC. 2001-02-13 US disclosed
EP-0850231-A1 PROCESS FOR PREPARING A 2-CHLORO-5-CHLOROMETHYL-THIAZOLE COMPOUND Novartis AG (CH) 1998-07-01 EP disclosed
WO-1997010226-A1 PROCESS FOR PREPARING A 2-CHLORO-5-CHLOROMETHYL-THIAZOLE COMPOUND NOVARTIS AG (CH) 1997-03-20 WO disclosed
EP-0033752-B1 PREPARATION OF 2-OXAZOLINES BY CYCLODEHYDRATION PROCESS EMPLOYING INORGANIC IRON SALTS AS CATALYSTS THE DOW CHEMICAL COMPANY (US) 1987-04-08 EP disclosed
US-4203900-A CYCLODEHYDRATION OF AN N-(2-HYDROXYALKYL)CARBOXAMIDE OR PRECURSOR WITH AN IRON COMPOUND CATALYST THE DOW CHEMICAL COMPANY (US) 1980-05-20 US disclosed