SCHEMBL5649591

SCHEMBL5649591

CCCCCCCCCCCCOc1ccccc1[S]

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.54
MEN1 O00255 1/20 0.54
NR1I2 O75469 1/20 0.54
CHRM2 P08172 1/20 0.54
CYP3A4 P08684 1/20 0.54
ADRA2A P08913 1/20 0.54
MAPT P10636 1/20 0.54
OPRK1 P41145 1/20 0.54
HTR2B P41595 1/20 0.54
SLC6A3 Q01959 1/20 0.54
KMT2A Q03164 1/20 0.54
HDAC6 Q9UBN7 1/20 0.54
CYP1A2 P05177 1/20 0.52
CYP2C9 P11712 1/20 0.52
CYP2C19 P33261 1/20 0.52
MCHR1 Q99705 2/20 0.46
TLR8 Q9NR97 2/20 0.46
LTA4H P09960 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.44
ALDH1A1 P00352 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1402312 1.00 LMNA (0.54) LMNAMEN1NR1I2CHRM2CYP3A4
SCHEMBL1402386 1.00 LMNA (0.54) LMNAMEN1NR1I2CHRM2CYP3A4
SCHEMBL6003210 0.98 CYP1A2 (0.53) LMNAMEN1NR1I2CHRM2CYP3A4
SCHEMBL543714 0.92 CYP1A2 (0.60) LMNAMEN1NR1I2CHRM2CYP3A4
SCHEMBL1402282 0.86 CYP1A2 (0.47) LMNAMEN1MAPTHTR2BKMT2A
SCHEMBL9387360 0.86 LMNA (0.62) LMNAMEN1NR1I2CHRM2CYP3A4
SCHEMBL2245919 0.86 LMNA (0.62) LMNAMEN1NR1I2CHRM2CYP3A4
SCHEMBL1964196 0.86 LMNA (0.62) LMNAMEN1NR1I2CHRM2CYP3A4
SCHEMBL1778134 0.86 LMNA (0.62) LMNAMEN1NR1I2CHRM2CYP3A4
SCHEMBL2859001 0.86 LMNA (0.62) LMNAMEN1NR1I2CHRM2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7196194-B2 Dye-forming coupler, silver halide photographic light-sensitive material and azomethine dye compound FUJI PHOTO FILM CO., LTD (JP) 2007-03-27 US disclosed
US-20040122238-A1 Dye-forming coupler, silver halide photographic light-sensitive material and azomethine dye compound FUJI PHOTO FILM CO., LTD. 2004-06-24 US disclosed
US-20040096787-A1 Dye-forming coupler, silver halide photographic light-sensitive material and azomethine dye compound FUJI PHOTO FILM CO., LTD. 2004-05-20 US disclosed
US-6727053-B2 FORMS AN AZOMETHINE DYE UPON A COUPLING REACTION WITH AN OXIDIZED PRODUCT OF A DEVELOPING AGENT FUJI PHOTO FILM CO., LTD. (JP) 2004-04-27 US disclosed
US-20030073047-A1 Dye-forming coupler, silver halide photographic light-sensitive material and azomethine dye compound FUJIFILM CORPORATION (JP) 2003-04-17 US disclosed
EP-1246006-A2 Dye-forming coupler, silver halide photographic light-sensitive material and azomethine dye compound FUJI PHOTO FILM CO., LTD. (JP) 2002-10-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030073047-A1 Dye-forming coupler, silver halide photographic light-sensitive material and azomethine dye compound CBR1, IK, CBR3 LMNA 1880/4885MEN1 195/4885NR1I2 743/4885
US-20040122238-A1 Dye-forming coupler, silver halide photographic light-sensitive material and azomethine dye compound CBR1, CBR3, IK LMNA 1594/4885MEN1 110/4885NR1I2 554/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.