Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 3/20 | 0.71 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.71 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | CA2 | P00918 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA7 | P43166 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17563119 | 0.91 | CYP4F2 (0.76) | CYP4F2CYP4A11MEP1BMAPTCA2 | |
| SCHEMBL12035616 | 0.87 | CYP4F2 (0.75) | CYP4F2CYP4A11MEP1BMAPTCA2 | |
| SCHEMBL4508966 | 0.87 | CYP4F2 (0.66) | CYP4F2CYP4A11MEP1BMAPTCA2 | |
| SCHEMBL9454406 | 0.86 | CYP4F2 (0.73) | CYP4F2CYP4A11MEP1BMAPTCA2 | |
| SCHEMBL12523791 | 0.86 | CYP4F2 (0.83) | CYP4F2CYP4A11MEP1BMAPTCA2 | |
| SCHEMBL129801 | 0.85 | CYP4F2 (0.71) | CYP4F2CYP4A11MEP1BMAPTCA2 | |
| SCHEMBL27475621 | 0.85 | CYP4F2 (0.54) | CYP4F2CYP4A11MEP1BMAPTRAB9A | |
| SCHEMBL321524 | 0.84 | CYP4F2 (0.71) | CYP4F2CYP4A11MEP1BMAPTCA2 | |
| SCHEMBL5544912 | 0.84 | CYP4F2 (0.71) | CYP4F2CYP4A11MEP1BMAPTCA2 | |
| SCHEMBL1793142 | 0.84 | CYP4F2 (0.81) | CYP4F2CYP4A11MEP1BMAPTCA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104016979-A | Substituted cyclic compound as well as use method and application thereof | GUANGDONG HEC PHARMACEUTICAL | 2014-09-03 | — | — | CN | disclosed |
| US-20070049620-A1 | Cyclic tertiary amine compound | SANKYO COMPANY, LIMITED (JP) | 2007-03-01 | — | — | US | disclosed |
| CN-1863793-A | Cyclic tertiary amine compound | SANKYO CO (JP) | 2006-11-15 | — | — | CN | disclosed |
| EP-1632488-A1 | CYCLIC TERTIARY AMINE COMPOUND | Sankyo Company, Limited (JP) | 2006-03-08 | — | — | EP | disclosed |
| EP-0683781-B1 | NOVEL INHIBITORS OF ADENOSINE MONOPHOSPHATE DEAMINASE | METABASIS THERAPEUTICS INC (US) | 2004-04-21 | — | — | EP | disclosed |
| US-5731432-A | Inhibitors of adenosine monophosphate deaminase | GENSIA SICOR INC. (US) | 1998-03-24 | — | — | US | disclosed |
| WO-1994018200-A1 | NOVEL INHIBITORS OF ADENOSINE MONOPHOSPHATE DEAMINASE | GENSIA, INC. (US) | 1994-08-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070049620-A1 | Cyclic tertiary amine compound | MYD88, IL5, BRD4 | CYP4F2 1436/4885CYP4A11 588/4885MEP1B 1427/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.