Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 1/20 | 0.56 |
| ▸ | PDE10A | Q9Y233 | 15/20 | 0.56 |
| ▸ | PDE3B | Q13370 | 13/20 | 0.49 |
| ▸ | PDE3A | Q14432 | 13/20 | 0.49 |
| ▸ | OXTR | P30559 | 1/20 | 0.43 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8231825 | 0.84 | PDE10A (0.70) | PDGFRBPDE10APDE3A | |
| SCHEMBL3056015 | 0.81 | PDE10A (0.56) | PDE10APDE3BPDE3AOXTRAVPR1A | |
| SCHEMBL4969825 | 0.80 | PDE10A (0.74) | PDGFRBPDE10APDE3A | |
| SCHEMBL4772060 | 0.80 | PDE10A (0.52) | PDGFRBPDE10A | |
| SCHEMBL4394817 | 0.78 | PDE10A (0.69) | PDGFRBPDE10APDE3BPDE3A | |
| SCHEMBL4969563 | 0.78 | PDE10A (0.56) | PDGFRBPDE10A | |
| SCHEMBL5245601 | 0.77 | PDE10A (0.53) | PDGFRBPDE10A | |
| SCHEMBL8233340 | 0.76 | PDE10A (0.54) | PDGFRBPDE10A | |
| SCHEMBL3053175 | 0.76 | LMNA (0.44) | PDE10APDE3BPDE3AOXTRAVPR1A | |
| SCHEMBL5911773 | 0.76 | PDE10A (0.58) | PDGFRBPDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070265270-A1 | Cinnoline derivatives as phosphodiesterase 10 inhibitors | MEMORY PHARMACEUTICALS CORPORATION | 2007-11-15 | — | — | US | disclosed |
| US-20070265270-A1 | Cinnoline derivatives as phosphodiesterase 10 inhibitors | MEMORY PHARMACEUTICALS CORPORATION | 2007-11-15 | — | — | US | disclosed |
| US-20070265270-A1 | Cinnoline derivatives as phosphodiesterase 10 inhibitors | MEMORY PHARMACEUTICALS CORPORATION | 2007-11-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070265270-A1 | Cinnoline derivatives as phosphodiesterase 10 inhibitors | PDE7A, PDE10A, PDE7B | PDGFRB 3311/4885PDE10A 2/4885PDE3B 6/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.