SCHEMBL5650758

SCHEMBL5650758

O=C(OC(=O)c1ccc(Cl)c(Cl)c1)c1ccc(Cl)c(Cl)c1

nearest known ligand 0.61

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.61
SRD5A2 P31213 1/20 0.53
MAPT P10636 2/20 0.51
KDM4E B2RXH2 2/20 0.50
KMT2A Q03164 2/20 0.50
MEN1 O00255 1/20 0.50
NPC1 O15118 1/20 0.50
PKM P14618 1/20 0.50
RAB9A P51151 1/20 0.50
HPGD P15428 3/20 0.48
ALDH1A1 P00352 1/20 0.47
AGTR1 P30556 1/20 0.47
POLB P06746 1/20 0.47
HTT P42858 1/20 0.47
KMO O15229 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29990540 1.00 TSHR (0.61) TSHRSRD5A2MAPTKDM4EKMT2A
SCHEMBL5650766 0.90 TSHR (0.57) TSHRSRD5A2MAPTKMT2AMEN1
SCHEMBL31120969 0.86 TSHR (0.61) TSHRSRD5A2MAPTKDM4EKMT2A
SCHEMBL27729553 0.86 TSHR (0.61) TSHRSRD5A2MAPTKDM4EKMT2A
SCHEMBL27299258 0.85 TSHR (0.50) TSHRSRD5A2MAPTKDM4EKMT2A
SCHEMBL249416 0.84 TSHR (0.59) TSHRSRD5A2MAPTKDM4EKMT2A
SCHEMBL30954395 0.84 TSHR (0.59) TSHRSRD5A2MAPTKDM4EKMT2A
SCHEMBL7531672 0.83 HSD17B10 (0.56) TSHRMAPTKDM4EKMT2AMEN1
SCHEMBL5393044 0.83 ALDH1A1 (0.64) TSHRMAPTKDM4EKMT2AMEN1
SCHEMBL6798278 0.83 TSHR (0.57) TSHRSRD5A2MAPTKDM4EKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117555204-B Negative photosensitive polyimide glue solution and glue film suitable for flexible circuit board 明士(北京)新材料开发有限公司 2024-04-26 CN claimed
CN-117555204-A Negative photosensitive polyimide glue solution and glue film suitable for flexible circuit board 明士(北京)新材料开发有限公司 2024-02-13 CN claimed
CN-117384378-A Photosensitive polyamic acid ester resin, resin composition, preparation method and application thereof 明士(北京)新材料开发有限公司 2024-01-12 CN claimed
CN-116577965-B Negative photosensitive solid adhesive film and preparation method thereof 明士(北京)新材料开发有限公司 2023-10-03 CN claimed
CN-116577965-A Negative photosensitive solid adhesive film and preparation method thereof 明士(北京)新材料开发有限公司 2023-08-11 CN claimed
CN-115407610-B Photosensitive resin composition, preparation method and application thereof 明士(北京)新材料开发有限公司 2023-05-16 CN claimed
CN-117555204-B Negative photosensitive polyimide glue solution and glue film suitable for flexible circuit board 明士(北京)新材料开发有限公司 2024-04-26 CN disclosed
CN-117430812-B Photosensitive polyamic acid ester resin, resin composition and application 明士(北京)新材料开发有限公司 2024-03-19 CN disclosed
CN-117555204-A Negative photosensitive polyimide glue solution and glue film suitable for flexible circuit board 明士(北京)新材料开发有限公司 2024-02-13 CN disclosed
CN-117430812-A Photosensitive polyamic acid ester resin, resin composition and application 明士(北京)新材料开发有限公司 2024-01-23 CN disclosed
CN-116577965-B Negative photosensitive solid adhesive film and preparation method thereof 明士(北京)新材料开发有限公司 2023-10-03 CN disclosed
CN-116577965-A Negative photosensitive solid adhesive film and preparation method thereof 明士(北京)新材料开发有限公司 2023-08-11 CN disclosed
CN-115407610-B Photosensitive resin composition, preparation method and application thereof 明士(北京)新材料开发有限公司 2023-05-16 CN disclosed
CN-115236938-A Negative photosensitive polyamic acid ester resin composition and use thereof 明士(北京)新材料开发有限公司 2022-10-25 CN disclosed
CN-115160569-A Photosensitive polyamic acid ester resin, resin composition and electronic component 明士(北京)新材料开发有限公司 2022-10-11 CN disclosed
US-7235559-B1 Therapeutic quinazoline derivatives ASTRAZENECA AB (SE) 2007-06-26 US disclosed
EP-1218355-A1 THERAPEUTIC QUINAZOLINE DERIVATIVES AstraZeneca AB (SE) 2002-07-03 EP disclosed
WO-2001021597-A1 THERAPEUTIC QUINAZOLINE DERIVATIVES ASTRAZENECA AB (SE) 2001-03-29 WO disclosed
US-4033989-A 9-Deoxy-PGF2 Analogs THE UPJOHN COMPANY (US) 1977-07-05 US disclosed
US-4018803-A 13,14-Didehydro-PG3 compounds THE UPJOHN COMPANY (US) 1977-04-19 US disclosed