Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.50 |
| ▸ | HPGD | P15428 | 7/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | CDC7 | O00311 | 2/20 | 0.47 |
| ▸ | DBF4 | Q9UBU7 | 2/20 | 0.47 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | GRM6 | O15303 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | DHODH | Q02127 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5648088 | 0.88 | MAPT (0.49) | ALDH1A1HPGDKDM4ESMN1; SMN2MAPT | |
| SCHEMBL2948992 | 0.82 | DHODH (0.51) | ALDH1A1HPGDKDM4ESMN1; SMN2MAPT | |
| SCHEMBL5648879 | 0.81 | KDM4E (0.41) | ALDH1A1HPGDKDM4EMAPTTDP1 | |
| SCHEMBL1266729 | 0.81 | MAPT (0.46) | ALDH1A1HPGDHSD17B10KDM4ESMN1; SMN2 | |
| SCHEMBL5653775 | 0.78 | CDC7 (0.41) | ALDH1A1HPGDHSD17B10KDM4ESMN1; SMN2 | |
| SCHEMBL1190734 | 0.77 | CDC7 (0.47) | MAPTCDC7DBF4TRPM8LMNA | |
| SCHEMBL16429545 | 0.74 | ALDH1A1 (0.55) | ALDH1A1HPGDHSD17B10KDM4ESMN1; SMN2 | |
| SCHEMBL10487739 | 0.74 | CDC7 (0.58) | ALDH1A1HPGDHSD17B10KDM4ESMN1; SMN2 | |
| SCHEMBL25205779 | 0.74 | HPGD (0.46) | ALDH1A1HPGDHSD17B10KDM4ESMN1; SMN2 | |
| SCHEMBL5650136 | 0.74 | MAPT (0.51) | ALDH1A1HPGDHSD17B10KDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7176215-B2 | Bicyclic oxopyridine and oxopyrimidine derivatives | CELLTECH R&D LIMITED (GB) | 2007-02-13 | — | — | US | disclosed |
| US-20040254200-A1 | Bicyclic oxopyridine and oxopyrimidine derivatives | UCB PHARMA S.A. (BE) | 2004-12-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040254200-A1 | Bicyclic oxopyridine and oxopyrimidine derivatives | MAPK1, ALK, NAT1 | ALDH1A1 1498/4885HPGD 1929/4885HSD17B10 3720/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.