Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.39 |
| ▸ | HPGDS | O60760 | 1/20 | 0.37 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.35 |
| ▸ | TUBB | P07437 | 2/20 | 0.35 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.35 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.35 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.35 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.35 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.35 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.35 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.35 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.35 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.35 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 0.35 |
| ▸ | TUBB6 | Q9BUF5 | 2/20 | 0.35 |
| ▸ | TUBB2B | Q9BVA1 | 2/20 | 0.35 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL97761 | 0.80 | CYP2A6 (0.57) | CYP2A6IMPDH2TUBB4ATUBBTUBA3C | |
| SCHEMBL28168668 | 0.78 | CYP2A6 (0.55) | CYP2A6IMPDH2TUBB4ATUBBTUBA3C | |
| Iodoform SCHEMBL28508578 | 0.77 | CYP2A6 (0.50) | CYP2A6IMPDH2TUBB4ATUBBTUBA3C | |
| Indole SCHEMBL2262674 | 0.75 | TRPA1 (0.53) | SLC7A5KDM4EMAPTAPAF1POLB | |
| Indole SCHEMBL22750244 | 0.75 | TRPA1 (0.53) | SLC7A5KDM4EMAPTAPAF1POLB | |
| Salicyladehyde SCHEMBL5555583 | 0.73 | TRIM24 (0.58) | SLC7A5MAPTMEN1LMNATSHR | |
| Hydrochloric Acid SCHEMBL30249045 | 0.72 | HTR1B (0.44) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| Valine SCHEMBL4155382 | 0.70 | SLC7A5 (0.54) | SLC7A5KDM4EMAPTMEN1LMNA | |
| SCHEMBL7971229 | 0.70 | PARP1 (0.46) | CYP2A6IMPDH2TUBB4ATUBBTUBA3C | |
| Carbazole SCHEMBL170807 | 0.69 | SLC7A5 (0.52) | SLC7A5KDM4EMAPTAPAF1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7230118-B2 | Process for the preparation of ropinirole | URQUIMA S.A. (ES) | 2007-06-12 | — | — | US | disclosed |
| US-20070032540-A1 | Process for the preparation of ropinirole | URGUIMA S.A. (ES) | 2007-02-08 | — | — | US | disclosed |
| EP-1673340-A1 | PROCESS FOR THE PREPARATION OF ROPINIROLE | Urquima S.A. (ES) | 2006-06-28 | — | — | EP | disclosed |
| WO-2005040115-A1 | PROCESS FOR THE PREPARATION OF ROPINIROLE | URQUIMA S.A. (ES) | 2005-05-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070032540-A1 | Process for the preparation of ropinirole | PRLHR, COMT, DRD4 | SLC7A5 2002/4885CYP2A6 599/4885IMPDH2 138/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.