Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.53 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.53 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.53 |
| ▸ | CD274 | Q9NZQ7 | 3/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | HPGDS | O60760 | 2/20 | 0.50 |
| ▸ | JAK1 | P23458 | 1/20 | 0.50 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5648986 | 0.90 | MAPK14 (0.55) | KDM4EALDH1A1SMN1; SMN2TSHRPOLB | |
| SCHEMBL5654047 | 0.86 | MAPK14 (0.51) | KDM4EALDH1A1SMN1; SMN2TSHRPOLB | |
| SCHEMBL5651511 | 0.85 | KDM4E (0.54) | KDM4EALDH1A1SMN1; SMN2TSHRPOLB | |
| SCHEMBL5652502 | 0.84 | CYP2C9 (0.61) | ALDH1A1SMN1; SMN2TSHRHPGD | |
| SCHEMBL5652458 | 0.84 | DRD3 (0.58) | ALDH1A1SMN1; SMN2TSHRMAPK1 | |
| SCHEMBL5649763 | 0.83 | TSHR (0.52) | KDM4EALDH1A1TSHRHPGDMAPK14 | |
| SCHEMBL5652001 | 0.82 | KDM4E (0.58) | KDM4EALDH1A1SMN1; SMN2TSHRPOLB | |
| SCHEMBL5649669 | 0.81 | MAPK8 (0.48) | KDM4E | |
| SCHEMBL5652999 | 0.80 | TSHR (0.56) | KDM4EALDH1A1SMN1; SMN2TSHRMAPK1 | |
| SCHEMBL14930175 | 0.80 | ERN1 (0.54) | ALDH1A1CD274HPGDHPGDS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7220769-B2 | Azolylbenzamides and analogues and their use for treating osteoporosis | NIKEM RESEARCH S.R.L. (IT) | 2007-05-22 | — | — | US | disclosed |
| US-20050038095-A1 | Azolylbenzamides and analogues and their use for treating osteoporosis | 3-V BIOSCIENCES, INC. | 2005-02-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050038095-A1 | Azolylbenzamides and analogues and their use for treating osteoporosis | NR0B2, NR0B1, NCOR1 | KDM4E 1605/4885ALDH1A1 2893/4885SMN1; SMN2 1510/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.