SCHEMBL5652175

SCHEMBL5652175

O=C(O)c1ccc(-c2ccc(O)cc2O)cc1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.61
HSD17B10 Q99714 2/20 0.58
CA12 O43570 3/20 0.58
CA1 P00915 3/20 0.58
CA2 P00918 3/20 0.58
CA7 P43166 3/20 0.58
CA9 Q16790 3/20 0.58
CA14 Q9ULX7 3/20 0.58
TYR P14679 2/20 0.58
CA4 P22748 2/20 0.58
CA6 P23280 2/20 0.58
CA3 P07451 1/20 0.58
DRD1 P21728 1/20 0.58
CA5A P35218 1/20 0.58
CA5B Q9Y2D0 1/20 0.58
ESR2 Q92731 1/20 0.54
MIF P14174 1/20 0.53
SRD5A2 P31213 2/20 0.52
EGFR P00533 1/20 0.52
HSD17B1 P14061 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28211489 0.88 HSD17B10 (0.58) ALOX5HSD17B10CA12CA1CA2
SCHEMBL3238016 0.88 CA12 (0.61) HSD17B10CA12CA1CA2CA7
SCHEMBL11739990 0.86 CA12 (0.56) ALOX5HSD17B10CA12CA1CA2
SCHEMBL29020927 0.86 CA12 (0.61) HSD17B10CA12CA1CA2CA7
SCHEMBL30702634 0.86 CA12 (0.56) ALOX5HSD17B10CA12CA1CA2
SCHEMBL29652627 0.86 CA12 (0.61) HSD17B10CA12CA1CA2CA7
SCHEMBL26981142 0.85 KDM4E (0.64) HSD17B10CA12CA1CA2CA7
SCHEMBL5653533 0.84 RARB (0.54) ALOX5HSD17B10ESR2MIFKDM4E
SCHEMBL12023160 0.83 CA12 (0.61) ALOX5HSD17B10CA12CA1CA2
SCHEMBL10717595 0.83 SRD5A2 (0.66) HSD17B10CA12CA1CA2CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170037248-A1 FLUORINATED RESORUFIN COMPOUNDS AND THEIR APPLICATION Life Technologies Corporation 2017-02-09 US disclosed
US-20170037248-A1 FLUORINATED RESORUFIN COMPOUNDS AND THEIR APPLICATION Life Technologies Corporation 2017-02-09 US disclosed
US-9212385-B2 Fluorinated resorufin compounds and their application Life Technologies Corporation (US) 2015-12-15 US disclosed
US-9212385-B2 Fluorinated resorufin compounds and their application Life Technologies Corporation (US) 2015-12-15 US disclosed
EP-1685117-B1 FLUORINATED RESORUFIN COMPOUNDS AND THEIR APPLICATION IN DETECTING HYDROGEN PEROXIDE LIFE TECHNOLOGIES CORP (US) 2015-01-07 EP disclosed
US-20140220612-A1 FLUORINATED RESORUFIN COMPOUNDS AND THEIR APPLICATION Life Technologies Corporation (US) 2014-08-07 US disclosed
US-20140220612-A1 FLUORINATED RESORUFIN COMPOUNDS AND THEIR APPLICATION Life Technologies Corporation (US) 2014-08-07 US disclosed
US-20130102014-A1 FLUORINATED RESORUFIN COMPOUNDS AND THEIR APPLICATION Life Technologies Corporation (US) 2013-04-25 US disclosed
US-20130102014-A1 FLUORINATED RESORUFIN COMPOUNDS AND THEIR APPLICATION Life Technologies Corporation (US) 2013-04-25 US disclosed
US-20110086341-A1 FLUORINATED RESORUFIN COMPOUNDS AND THEIR APPLICATION Life Technologies Corporation (US) 2011-04-14 US disclosed
US-7875261-B2 Fluorinated resorufin compounds and their application Life Technologies Corporation (US) 2011-01-25 US disclosed
US-7432372-B2 for detecting reactive oxygen species, e.g., hydrogen peroxide; used in immunology, diagnostics, molecular biology and fluorescence based assays INVITROGEN CORPORATION (US) 2008-10-07 US disclosed
US-7432372-B2 for detecting reactive oxygen species, e.g., hydrogen peroxide; used in immunology, diagnostics, molecular biology and fluorescence based assays INVITROGEN CORPORATION (US) 2008-10-07 US disclosed
US-20080113341-A1 Staining; for detecting reactive oxygen species such as hydrogen peroxide; used in immunology, diagnostics, molecular biology and fluorescence based assays INVITROGEN CORPORATION (US) 2008-05-15 US disclosed
US-20080113341-A1 Staining; for detecting reactive oxygen species such as hydrogen peroxide; used in immunology, diagnostics, molecular biology and fluorescence based assays INVITROGEN CORPORATION (US) 2008-05-15 US disclosed
US-20060257917-A1 FLUORESCENT DYES, ENERGY TRANSFER COUPLES AND METHODS MILLIPORE CORPORATION 2006-11-16 US disclosed
US-7091348-B2 Fluorescent dyes, energy transfer couples and methods GUAVA TECHNOLOGIES, INC. (US) 2006-08-15 US disclosed
EP-1539728-A2 FLUORESCENT DYES, ENERGY TRANSFER COUPLES AND METHODS Guava Technologies, Inc. (US) 2005-06-15 EP disclosed
US-20040073014-A1 Fluorescent dyes, energy transfer couples and methods EMD MILLIPORE CORPORATION 2004-04-15 US disclosed
WO-2004003510-A2 FLUORESCENT DYES, ENERGY TRANSFER COUPLES AND METHODS GUAVA TECHNOLOGIES, INC. (US) 2004-01-08 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110086341-A1 FLUORINATED RESORUFIN COMPOUNDS AND THEIR APPLICATION CYP2F1, CYP4F2, CYP4F3 ALOX5 292/4885HSD17B10 325/4885CA12 4816/4885
US-20060257917-A1 FLUORESCENT DYES, ENERGY TRANSFER COUPLES AND METHODS TIMM50, TIMM44, APEX1 ALOX5 3353/4885HSD17B10 556/4885CA12 4094/4885
US-20170037248-A1 FLUORINATED RESORUFIN COMPOUNDS AND THEIR APPLICATION CYP2F1, CYP4F2, CYP4F3 ALOX5 292/4885HSD17B10 325/4885CA12 4816/4885
US-20130102014-A1 FLUORINATED RESORUFIN COMPOUNDS AND THEIR APPLICATION CYP2F1, CYP4F2, CYP4F3 ALOX5 292/4885HSD17B10 325/4885CA12 4816/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.