Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 4/20 | 0.61 |
| ▸ | CA1 | P00915 | 4/20 | 0.61 |
| ▸ | CA2 | P00918 | 4/20 | 0.61 |
| ▸ | CA9 | Q16790 | 4/20 | 0.61 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.61 |
| ▸ | CA4 | P22748 | 3/20 | 0.61 |
| ▸ | CA6 | P23280 | 3/20 | 0.61 |
| ▸ | CA7 | P43166 | 3/20 | 0.61 |
| ▸ | MAPT | P10636 | 2/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | GAA | P10253 | 1/20 | 0.61 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.51 |
| ▸ | EGFR | P00533 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26981142 | 0.98 | KDM4E (0.64) | CA12CA1CA2CA9CA14 | |
| SCHEMBL28211489 | 0.92 | HSD17B10 (0.58) | CA12CA1CA2CA9CA14 | |
| SCHEMBL3663963 | 0.89 | POLB (0.59) | CA12CA1CA2CA9CA14 | |
| SCHEMBL2558827 | 0.88 | HSD17B1 (0.57) | CA12CA1CA2CA9CA14 | |
| SCHEMBL5937383 | 0.88 | SRD5A2 (0.58) | CA12CA1CA2CA9CA14 | |
| SCHEMBL4428101 | 0.88 | BCL2L1 (0.62) | CA12CA1CA2CA9CA14 | |
| SCHEMBL5652175 | 0.88 | ALOX5 (0.61) | CA12CA1CA2CA9CA14 | |
| SCHEMBL28085220 | 0.87 | KDM4E (0.52) | CA12CA1CA2CA9CA14 | |
| SCHEMBL29133892 | 0.86 | TP53 (0.57) | CA12CA1CA2CA9CA14 | |
| SCHEMBL2771199 | 0.86 | CA12 (0.73) | CA12CA1CA2CA9CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113801336-B | Functionalization of metal organic framework material UiO-67-4Me, functionalized product and application thereof | 中山大学 | 2022-06-24 | — | — | CN | claimed |
| CN-113801336-A | Functionalization of metal organic framework material UiO-67-4Me, functionalized product and application thereof | 中山大学 | 2021-12-17 | — | — | CN | claimed |
| US-8188316-B2 | Integrated process for the preparation of polybenzimidazole precursors | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2012-05-29 | — | — | US | claimed |
| US-20100160679-A1 | INTEGRATED PROCESS FOR THE PREPARATION OF POLYBENZIMIDAZOLE PRECURSORS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2010-06-24 | — | — | US | claimed |
| CN-113801336-B | Functionalization of metal organic framework material UiO-67-4Me, functionalized product and application thereof | 中山大学 | 2022-06-24 | — | — | CN | disclosed |
| CN-113801336-A | Functionalization of metal organic framework material UiO-67-4Me, functionalized product and application thereof | 中山大学 | 2021-12-17 | — | — | CN | disclosed |
| US-20210154625-A1 | THIN FILM NANOCOMPOSITE MEMBRANES CONTAINING METAL-ORGANIC CAGES FOR DESALINATION | NATIONAL UNIVERSITY OF SINGAPORE (SG) | 2021-05-27 | — | — | US | disclosed |
| CN-108456218-B | Rare earth-organic porous material, preparation method thereof and application thereof in detection of neurological disease marker glutamic acid | 浙江大学 | 2020-03-17 | — | — | CN | disclosed |
| US-8188316-B2 | Integrated process for the preparation of polybenzimidazole precursors | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2012-05-29 | — | — | US | disclosed |
| US-20100160679-A1 | INTEGRATED PROCESS FOR THE PREPARATION OF POLYBENZIMIDAZOLE PRECURSORS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2010-06-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100160679-A1 | INTEGRATED PROCESS FOR THE PREPARATION OF POLYBENZIMIDAZOLE PRECURSORS | DDC, DDT, PDCD2L | CA12 2175/4885CA1 2537/4885CA2 1415/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.