Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT3 | P36888 | 6/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5647628 | 0.88 | LMNA (0.35) | KDM4ETSHR | |
| SCHEMBL5649572 | 0.85 | TSHR (0.51) | TSHR | |
| SCHEMBL5652193 | 0.79 | FLT3 (0.41) | FLT3 | |
| SCHEMBL5648377 | 0.76 | FLT3 (0.39) | FLT3KDM4EHSD17B10 | |
| SCHEMBL5651885 | 0.76 | FLT3 (0.45) | FLT3 | |
| SCHEMBL5653312 | 0.74 | FLT3 (0.46) | FLT3KDM4EHSD17B10 | |
| SCHEMBL5652607 | 0.73 | FLT3 (0.45) | FLT3 | |
| SCHEMBL5651507 | 0.73 | FLT3 (0.45) | FLT3 | |
| SCHEMBL5649910 | 0.71 | FLT3 (0.42) | FLT3 | |
| SCHEMBL5651989 | 0.71 | FLT3 (0.45) | FLT3KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7220769-B2 | Azolylbenzamides and analogues and their use for treating osteoporosis | NIKEM RESEARCH S.R.L. (IT) | 2007-05-22 | — | — | US | disclosed |