SCHEMBL565225

SCHEMBL565225

CC#Cc1ccc(C(=O)O)cn1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
P4HA1 P13674 2/20 0.52
P4HTM Q9NXG6 2/20 0.52
MIF P14174 1/20 0.50
GRM5 P41594 4/20 0.49
HCAR3 P49019 6/20 0.49
GABRP O00591 1/20 0.48
GABRD O14764 1/20 0.48
GABRA1 P14867 1/20 0.48
GABRB1 P18505 1/20 0.48
GABRG2 P18507 1/20 0.48
GABRB3 P28472 1/20 0.48
GABRA5 P31644 1/20 0.48
GABRA3 P34903 1/20 0.48
GABRA2 P47869 1/20 0.48
GABRB2 P47870 1/20 0.48
GABRA4 P48169 1/20 0.48
GABRE P78334 1/20 0.48
GABRA6 Q16445 1/20 0.48
GABRG1 Q8N1C3 1/20 0.48
GABRG3 Q99928 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7608655 0.82 P4HA1 (0.48) P4HA1P4HTMMIFGRM5HCAR3
SCHEMBL4081970 0.81 P4HA1 (0.47) P4HA1P4HTMMIFGRM5HCAR3
SCHEMBL16673635 0.80 P4HA1 (0.46) P4HA1P4HTMMIFGRM5HCAR3
SCHEMBL29470887 0.79 P4HA1 (0.48) P4HA1P4HTMMIFGRM5HCAR3
SCHEMBL7527125 0.79 GRM5 (0.77) P4HA1P4HTMGRM5CYP26A1CYP3A4
SCHEMBL29470888 0.79 P4HA1 (0.48) P4HA1P4HTMMIFGRM5HCAR3
SCHEMBL7611057 0.79 P4HA1 (0.57) P4HA1P4HTMMIFGRM5HCAR3
SCHEMBL31371654 0.79 P4HA1 (0.57) P4HA1P4HTMMIFGRM5HCAR3
SCHEMBL5163246 0.79 P4HA1 (0.57) P4HA1P4HTMMIFGRM5HCAR3
SCHEMBL6411960 0.77 KMT2A (0.52) ALDH1A1CYP1A2CYP2C9HPGDCYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022078279-A1 ANTIBODY-DRUG CONJUGATE AND USE THEREOF 昆山新蕴达生物科技有限公司 2022-04-21 WO disclosed
US-9181182-B2 S1P receptors modulators AKAAL PHARMA PTY LTD (AU) 2015-11-10 US disclosed
US-20120034270-A1 S1P Receptors Modulators AKAAL PHARMA PTY LTD (AU) 2012-02-09 US disclosed
EP-2344446-A1 S1P RECEPTORS MODULATORS Akaal Pharma Pty Ltd (AU) 2011-07-20 EP disclosed
WO-2010042998-A1 S1P RECEPTORS MODULATORS AKAAL PHARMA PTY LTD (AU) 2010-04-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120034270-A1 S1P Receptors Modulators S1PR1, S1PR5, S1PR3 P4HA1 2920/4885P4HTM 1967/4885MIF 677/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.