Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 8/20 | 0.46 |
| ▸ | NPC1 | O15118 | 8/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.46 |
| ▸ | RELA | Q04206 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 5/20 | 0.46 |
| ▸ | CA9 | Q16790 | 5/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5652329 | 1.00 | RAB9A (0.46) | RAB9ANPC1ALDH1A1NPSR1SMN1; SMN2 | |
| SCHEMBL5238262 | 0.94 | NPC1 (0.39) | RAB9ANPC1ALDH1A1NPSR1SMN1; SMN2 | |
| SCHEMBL5232093 | 0.94 | NPC1 (0.39) | RAB9ANPC1ALDH1A1NPSR1SMN1; SMN2 | |
| SCHEMBL5232099 | 0.94 | NPC1 (0.39) | RAB9ANPC1ALDH1A1NPSR1SMN1; SMN2 | |
| SCHEMBL5238271 | 0.94 | NPC1 (0.39) | RAB9ANPC1ALDH1A1NPSR1SMN1; SMN2 | |
| SCHEMBL5231275 | 0.93 | CA12 (0.40) | RAB9ANPC1ALDH1A1NPSR1SMN1; SMN2 | |
| SCHEMBL5235387 | 0.93 | NPC1 (0.46) | RAB9ANPC1ALDH1A1NPSR1SMN1; SMN2 | |
| SCHEMBL5229964 | 0.93 | NPC1 (0.45) | RAB9ANPC1ALDH1A1NPSR1SMN1; SMN2 | |
| SCHEMBL5229973 | 0.93 | NPC1 (0.45) | RAB9ANPC1ALDH1A1NPSR1SMN1; SMN2 | |
| SCHEMBL5235380 | 0.93 | NPC1 (0.46) | RAB9ANPC1ALDH1A1NPSR1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070167507-A1 | 4-Carbox pyrazole derivatives useful as anti-viral agents | GLAXO GROUP LIMITED (GB) | 2007-07-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070167507-A1 | 4-Carbox pyrazole derivatives useful as anti-viral agents | HAVCR2, RPL35, ZC3HAV1L | RAB9A 1879/4885NPC1 352/4885ALDH1A1 1138/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.