Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 4/20 | 0.50 |
| ▸ | TAOK3 | Q9H2K8 | 4/20 | 0.47 |
| ▸ | TAOK1 | Q7L7X3 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | DHODH | Q02127 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | CFD | P00746 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5652383 | 0.83 | EPHX2 (0.56) | EPHX2TAOK3TAOK1ALDH1A1HTT | |
| SCHEMBL5654193 | 0.83 | TAOK3 (0.56) | TAOK3TAOK1ALDH1A1HTTKDM4E | |
| SCHEMBL5651524 | 0.80 | TAOK3 (0.50) | EPHX2TAOK3TAOK1ALDH1A1HTT | |
| SCHEMBL14422180 | 0.76 | TAOK3 (0.73) | EPHX2TAOK3TAOK1ALDH1A1HTT | |
| SCHEMBL5651521 | 0.73 | TAOK3 (0.58) | EPHX2TAOK3TAOK1ALDH1A1HTT | |
| SCHEMBL5654930 | 0.72 | ALDH1A1 (0.51) | ALDH1A1HTTKDM4ECFD | |
| SCHEMBL5653436 | 0.70 | ALDH1A1 (0.64) | TAOK3TAOK1ALDH1A1HTT | |
| SCHEMBL5653425 | 0.70 | ALDH1A1 (0.64) | TAOK3TAOK1ALDH1A1HTT | |
| SCHEMBL5654660 | 0.70 | TAOK1 (0.62) | TAOK3TAOK1ALDH1A1HTTL3MBTL1 | |
| SCHEMBL7048944 | 0.69 | KDM4E (0.63) | TAOK3TAOK1ALDH1A1HTTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070208166-A1 | Tao Kinase Modulators And Method Of Use | EXELIXIS, INC. (US) | 2007-09-06 | — | — | US | claimed |
| US-20070208166-A1 | Tao Kinase Modulators And Method Of Use | EXELIXIS, INC. (US) | 2007-09-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070208166-A1 | Tao Kinase Modulators And Method Of Use | TAOK1, TAOK3, MAP3K6 | EPHX2 3128/4885TAOK3 2/4885TAOK1 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.