Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | NOS3 | P29474 | 1/20 | 0.30 |
| ▸ | NOS1 | P29475 | 1/20 | 0.30 |
| ▸ | NOS2 | P35228 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5379768 | 1.00 | ALDH1A1 (0.44) | ALDH1A1NOS3NOS1NOS2 | |
| SCHEMBL7844516 | 1.00 | ALDH1A1 (0.44) | ALDH1A1NOS3NOS1NOS2 | |
| SCHEMBL7854415 | 1.00 | ALDH1A1 (0.44) | ALDH1A1NOS3NOS1NOS2 | |
| SCHEMBL7853235 | 0.97 | ALDH1A1 (0.47) | ALDH1A1NOS3NOS1NOS2 | |
| SCHEMBL9821231 | 0.92 | ALDH1A1 (0.39) | ALDH1A1NOS3NOS1NOS2 | |
| SCHEMBL7845053 | 0.92 | — | — | |
| SCHEMBL7856882 | 0.92 | ALDH1A1 (0.39) | ALDH1A1NOS3NOS1NOS2 | |
| SCHEMBL7853346 | 0.89 | ALDH1A1 (0.44) | ALDH1A1NOS3NOS1NOS2 | |
| SCHEMBL1366434 | 0.89 | ALDH1A1 (0.44) | ALDH1A1NOS3NOS1NOS2 | |
| SCHEMBL11221870 | 0.89 | ALDH1A1 (0.44) | ALDH1A1NOS3NOS1NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070265270-A1 | Cinnoline derivatives as phosphodiesterase 10 inhibitors | MEMORY PHARMACEUTICALS CORPORATION | 2007-11-15 | — | — | US | claimed |
| US-20070265270-A1 | Cinnoline derivatives as phosphodiesterase 10 inhibitors | MEMORY PHARMACEUTICALS CORPORATION | 2007-11-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070265270-A1 | Cinnoline derivatives as phosphodiesterase 10 inhibitors | PDE7A, PDE10A, PDE7B | ALDH1A1 416/4885NOS3 495/4885NOS1 302/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.