SCHEMBL565259

SCHEMBL565259

Nc1ccc(S(=O)(=O)c2ccc(O)c(N)c2)cc1

nearest known ligand 0.85

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 3/20 0.85
MAPT P10636 2/20 0.85
ALDH1A1 P00352 4/20 0.69
HTR6 P50406 3/20 0.69
PKM P14618 3/20 0.69
CA1 P00915 4/20 0.66
CA2 P00918 4/20 0.66
CA12 O43570 3/20 0.66
CA9 Q16790 3/20 0.66
HSD17B10 Q99714 2/20 0.63
TSHR P16473 3/20 0.61
LMNA P02545 2/20 0.61
CYP2C9 P11712 2/20 0.61
MPO P05164 1/20 0.61
CYP3A4 P08684 1/20 0.61
NPC1 O15118 1/20 0.55
MEN1 O00255 2/20 0.52
KMT2A Q03164 2/20 0.52
HKDC1 Q2TB90 1/20 0.49
CA14 Q9ULX7 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29871288 0.92 GAA (1.00) GAAMAPTALDH1A1HTR6PKM
SCHEMBL29363328 0.92 GAA (1.00) GAAMAPTALDH1A1HTR6PKM
SCHEMBL1732796 0.92 GAA (1.00) GAAMAPTALDH1A1HTR6PKM
SCHEMBL109925 0.92 GAA (1.00) GAAMAPTALDH1A1HTR6PKM
SCHEMBL28269760 0.90 GAA (0.96) GAAMAPTALDH1A1HTR6PKM
Hydrochloric Acid SCHEMBL28556898 0.90 GAA (0.96) GAAMAPTALDH1A1HTR6PKM
Hydrochloric Acid SCHEMBL9447766 0.90 GAA (0.96) GAAMAPTALDH1A1HTR6PKM
SCHEMBL565062 0.89 GAA (0.85) GAAMAPTALDH1A1HTR6PKM
Hydrochloric Acid SCHEMBL9169331 0.88 GAA (0.92) GAAMAPTALDH1A1HTR6PKM
Hydrochloric Acid SCHEMBL9180895 0.88 GAA (0.92) GAAMAPTALDH1A1HTR6PKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8674029-B2 Method of preparing stabilized polymeric systems using polymeric peroxides Sunocs LLC (US) 2014-03-18 US disclosed
US-20120035307-A1 PROCESS FOR MAKING STABLIZED POLYMERIC SYSTEMS WITH NANOSTRUCTURES SONG CHENGQIAN (US) 2012-02-09 US disclosed
US-20120035315-A1 METHOD OF PREPARING STABLIZED POLYMERIC SYSTEMS USING POLYMERIC PEROXIDES SONG CHENGQIAN (US) 2012-02-09 US disclosed
US-7498467-B2 Antioxidant and bisaminophenol derivative IDEMITSU KOSAN CO., LTD. (JP) 2009-03-03 US disclosed
US-20080161608-A1 ANTIOXIDANT AND BISAMINOPHENOL DERIVATIVE IDEMITSU KOSAN CO., LTD. (JP) 2008-07-03 US disclosed
US-20060208227-A1 Antioxidant and bisaminophenol derivative IDEMITSU LOSAN CO., LTD (JP) 2006-09-21 US disclosed
EP-1612254-A1 ANTIOXIDANT AND BISAMINOPHENOL DERIVATIVE IDEMITSU KOSAN COMPANY LIMITED (JP) 2006-01-04 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080161608-A1 ANTIOXIDANT AND BISAMINOPHENOL DERIVATIVE CBR1, CBR3, HMOX1 GAA 3993/4885MAPT 3886/4885ALDH1A1 204/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.