Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.53 |
| ▸ | RAB9A | P51151 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | PPARG | P37231 | 1/20 | 0.51 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.51 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.50 |
| ▸ | HTR3B | O95264 | 1/20 | 0.50 |
| ▸ | HTR3A | P46098 | 1/20 | 0.50 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.50 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.50 |
| ▸ | CNR1 | P21554 | 13/20 | 0.47 |
| ▸ | CNR2 | P34972 | 12/20 | 0.47 |
| ▸ | FAAH | O00519 | 6/20 | 0.47 |
| ▸ | ABHD12 | Q8N2K0 | 3/20 | 0.45 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.43 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.43 |
| ▸ | TAS1R2 | Q8TE23 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5534556 | 0.84 | CNR2 (0.58) | CNR1CNR2FAAHABHD12 | |
| SCHEMBL5528757 | 0.82 | NPC1 (0.73) | NPC1RAB9AALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL5524624 | 0.79 | NPC1 (0.72) | NPC1RAB9AALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL5526109 | 0.76 | CNR1 (0.64) | NPC1RAB9AGAAPPARGNCOA2 | |
| SCHEMBL5527487 | 0.75 | CNR2 (0.60) | CNR1CNR2FAAHABHD12 | |
| SCHEMBL5530075 | 0.72 | CNR2 (0.64) | NPC1RAB9AGAAPPARGNCOA2 | |
| SCHEMBL14376426 | 0.71 | NPC1 (0.72) | NPC1RAB9AALDH1A1HPGDGAA | |
| SCHEMBL5529629 | 0.70 | NPC1 (0.71) | NPC1RAB9AALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL5527500 | 0.69 | CNR2 (0.65) | NPC1RAB9AGAAPPARGNCOA2 | |
| SCHEMBL24937540 | 0.69 | CNR1 (0.85) | CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070054923-A1 | Inhibitors of macrophage migration inhibitory factor and methods for identifying the same | AVANIR PHARMACEUTICALS | 2007-03-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070054923-A1 | Inhibitors of macrophage migration inhibitory factor and methods for identifying the same | MIF, MSR1, MMP12 | NPC1 705/4885RAB9A 2899/4885ALDH1A1 1799/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.