Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | IKBKB | O14920 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | IAPP | P10997 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | MPO | P05164 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27631244 | 0.79 | HTR2C (0.44) | HTTALDH1A1CYP1A2CYP2C19CYP3A4 | |
| SCHEMBL1250315 | 0.76 | MAPT (0.66) | SMN1; SMN2HTTGLAALDH1A1MAPT | |
| SCHEMBL29611317 | 0.76 | MAPT (0.66) | SMN1; SMN2HTTGLAALDH1A1MAPT | |
| SCHEMBL28753609 | 0.71 | AHR (0.32) | MAPTMEN1KMT2ACYP3A4 | |
| SCHEMBL6015904 | 0.71 | ALDH1A1 (0.57) | SMN1; SMN2HTTALDH1A1MAPTCYP2C19 | |
| SCHEMBL10344942 | 0.71 | ALDH1A1 (0.68) | SMN1; SMN2ALDH1A1MAPTCYP1A2CYP2C19 | |
| SCHEMBL6015984 | 0.69 | ALDH1A1 (0.59) | HTTALDH1A1MAPTCYP2C19MEN1 | |
| SCHEMBL3871239 | 0.68 | ATM (0.54) | ALDH1A1MAPTKMT2ATSHRKDM4E | |
| SCHEMBL6015920 | 0.68 | ALDH1A1 (0.39) | SMN1; SMN2HTTALDH1A1MAPTCYP1A2 | |
| SCHEMBL5497510 | 0.68 | ATM (0.47) | CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070254917-A1 | INTRACELLULAR RECEPTOR MODULATOR COMPOUNDS AND METHODS | LIGAND PHARMACEUTICALS INC. | 2007-11-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070254917-A1 | INTRACELLULAR RECEPTOR MODULATOR COMPOUNDS AND METHODS | CASR, GRK2, RYR2 | SMN1; SMN2 4292/4885HTT 2408/4885IKBKB 490/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.