SCHEMBL5652837

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5649893	0.84	EGFR (0.64)	EGFRSRCRIPK2NOD1KDR
	SCHEMBL7116324	0.84	SRC (0.75)	EGFRSRCRIPK2NOD1KDR
	SCHEMBL5649023	0.83	EGFR (0.62)	EGFRSRCRIPK2NOD1KDR
	SCHEMBL5649183	0.83	EGFR (0.62)	EGFRSRCRIPK2NOD1KDR
	SCHEMBL5652519	0.83	EGFR (0.72)	EGFRSRCKDREPHB4EPHA2
	SCHEMBL5649175	0.83	KDR (0.79)	EGFRSRCRIPK2KDRRET
	SCHEMBL6944605	0.83	EGFR (1.00)	EGFRSRCRIPK2NOD1KDR
	SCHEMBL5648329	0.83	EGFR (0.61)	EGFRSRCRIPK2NOD1KDR
	Hydrochloric Acid SCHEMBL28028278	0.82	EGFR (0.80)	EGFRSRCRIPK2NOD1KDR
	SCHEMBL5648497	0.82	EPHA2 (0.73)	EGFRSRCRIPK2NOD1KDR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.