SCHEMBL565298

SCHEMBL565298

Nc1cccc(-c2ccccc2)c1O

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.62
HSD17B10 Q99714 3/20 0.62
HDAC4 P56524 1/20 0.54
HDAC2 Q92769 1/20 0.54
HDAC8 Q9BY41 1/20 0.54
HDAC6 Q9UBN7 1/20 0.54
HNF4A P41235 1/20 0.53
HPGD P15428 2/20 0.50
BCL2L1 Q07817 1/20 0.50
MMP2 P08253 1/20 0.47
BACE1 P56817 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
BRD4 O60885 1/20 0.46
NR1I2 O75469 1/20 0.46
SMARCA2 P51531 1/20 0.46
SMARCA4 P51532 1/20 0.46
PBRM1 Q86U86 1/20 0.46
ALOX15 P16050 2/20 0.42
TSHR P16473 1/20 0.42
KDM4E B2RXH2 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30646075 1.00 ALDH1A1 (0.62) ALDH1A1HSD17B10HDAC4HDAC2HDAC8
SCHEMBL3788816 0.84 ALDH1A1 (0.43) ALDH1A1HSD17B10HDAC4HDAC2HDAC8
SCHEMBL29442586 0.84 ABL1 (0.47) ALDH1A1HSD17B10BCL2L1MMP2MEN1
SCHEMBL8724544 0.84 HSD17B10 (0.52) ALDH1A1HSD17B10HDAC4HDAC2HDAC8
SCHEMBL30605196 0.83 HDAC4 (0.65) ALDH1A1HSD17B10HDAC4HDAC2HDAC8
SCHEMBL565923 0.83 ALDH1A1 (0.50) ALDH1A1HSD17B10HPGDMMP2L3MBTL1
SCHEMBL60283 0.83 HDAC4 (0.65) ALDH1A1HSD17B10HDAC4HDAC2HDAC8
SCHEMBL30175420 0.83 ALDH1A1 (0.50) ALDH1A1HSD17B10HPGDMMP2L3MBTL1
Hydrochloric Acid SCHEMBL30171386 0.83 ABL1 (0.45) ALDH1A1HSD17B10BCL2L1MMP2MEN1
SCHEMBL3782730 0.81 ALDH1A1 (0.65) ALDH1A1HSD17B10HPGDMMP2L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 104 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105085276-A Eltrombopag intermediate and preparation method therefor and application thereof SHANGHAI INST PHARM INDUSTRY 2015-11-25 CN claimed
CN-105085287-A Preparation method of 3'-amino-2'-hydroxy-[1,1'-biphenyl]-3-carboxylic acid SHANGHAI INST PHARM INDUSTRY 2015-11-25 CN claimed
US-4192682-A NON-DIFFUSIBLE COMPOUND HAVING OXIDATION POWER ON A HYDROQUINONE DEVELOPING AGENT; DEVELOPER CONTAINING NO HYDROQUINONE KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1980-03-11 US claimed
EP-4273125-A1 HETEROCYCLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME, AND ELECTRONIC APPARATUS INCLUDING THE ORGANIC LIGHT-EMITTING DEVICE Samsung Electronics Co., Ltd. (KR) 2023-11-08 EP disclosed
CN-105324438-B Light resistance improver 大赛璐赢创株式会社 2020-11-06 CN disclosed
EP-3502193-B1 MOULDED BODY COMPRISING A LIGHT-RESISTANT RESIN COMPOSITION DAICEL EVONIK LTD (JP) 2020-03-18 EP disclosed
EP-3502193-A1 MOULDED BODY COMPRISING A LIGHT-RESISTANT RESIN COMPOSITION Daicel-Evonik Ltd. (JP) 2019-06-26 EP disclosed
EP-2987833-B1 LIGHT-RESISTANT RESIN COMPOSITION, AND MOULDED BODY THEREOF DAICEL EVONIK LTD (JP) 2019-06-12 EP disclosed
US-10246586-B2 Light-resistance improver DAICEL-EVONIK LTD. (JP) 2019-04-02 US disclosed
EP-2987832-B1 USE OF FLUORORESIN AS LIGHT-RESISTANCE IMPROVER DAICEL EVONIK LTD (JP) 2019-02-06 EP disclosed
CN-108101845-A A kind of preparation method of Ai Qu pools pa 苏州科伦药物研究有限公司 2018-06-01 CN disclosed
EP-0181728-A2 Light-sensitive silver halide photographic material KONICA CORPORATION (JP) 1986-05-21 EP disclosed
CN-85108256-A LIGHT-SENSITIVE SILVER HALIDE PHOTOGRAPHIC MATERIAL 1986-05-10 CN disclosed
US-4581327-A CORE AND SHELL STRUCTURES, RHODIUM DOPED SHELLS, HARDNESS OF TONE, STORAGE STABILITY KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1986-04-08 US disclosed
EP-0146302-A1 Light-sensitive silver halide photographic material for direct-post and method for processing the same KONICA CORPORATION (JP) 1985-06-26 EP disclosed
US-4444875-A LAYER OF A TETRAZOLIUM COMPOUND KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1984-04-24 US disclosed
US-4329417-A OXIDIZERS AND QUATERNARY AMMONIUM SALTS, PHOSPHONIUM SALTS OR SULFONIUM SALTS KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1982-05-11 US disclosed
US-4211835-A TETRAZOLIUM COMPOUND, BLACK AND WHITE, HIGH CONTRAST KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1980-07-08 US disclosed
US-4208513-A Benzoxazolyl-phenylstilbenes, processes for producing them, and their use as optical brighteners CIBA-GEIGY CORPORATION (US) 1980-06-17 US disclosed
US-4192682-A NON-DIFFUSIBLE COMPOUND HAVING OXIDATION POWER ON A HYDROQUINONE DEVELOPING AGENT; DEVELOPER CONTAINING NO HYDROQUINONE KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1980-03-11 US disclosed