Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.64 |
| ▸ | TAOK3 | Q9H2K8 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.46 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5652174 | 0.84 | TAOK3 (0.61) | TAOK1TAOK3KMT2AALDH1A1MAPT | |
| SCHEMBL5652656 | 0.84 | TAOK1 (0.61) | TAOK1TAOK3KMT2AALDH1A1MAPT | |
| SCHEMBL5653045 | 0.84 | TAOK1 (0.68) | TAOK1TAOK3KMT2AMEN1ALDH1A1 | |
| SCHEMBL5652352 | 0.84 | TAOK1 (0.62) | TAOK1TAOK3KMT2AMEN1ALDH1A1 | |
| SCHEMBL5654660 | 0.83 | TAOK1 (0.62) | TAOK1TAOK3KMT2AALDH1A1MAPT | |
| SCHEMBL31458364 | 0.78 | TAOK1 (1.00) | TAOK1TAOK3KMT2AMEN1ALDH1A1 | |
| SCHEMBL14422169 | 0.78 | TAOK1 (1.00) | TAOK1TAOK3KMT2AMEN1ALDH1A1 | |
| SCHEMBL15131136 | 0.73 | KMT2A (0.57) | TAOK1TAOK3KMT2AMEN1ALDH1A1 | |
| SCHEMBL5654930 | 0.71 | ALDH1A1 (0.51) | KMT2AMEN1ALDH1A1MAPTLMNA | |
| SCHEMBL6252377 | 0.69 | KMT2A (0.68) | TAOK1TAOK3KMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070208166-A1 | Tao Kinase Modulators And Method Of Use | EXELIXIS, INC. (US) | 2007-09-06 | — | — | US | claimed |
| US-20070208166-A1 | Tao Kinase Modulators And Method Of Use | EXELIXIS, INC. (US) | 2007-09-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070208166-A1 | Tao Kinase Modulators And Method Of Use | TAOK1, TAOK3, MAP3K6 | TAOK1 1/4885TAOK3 2/4885KMT2A 2240/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.