⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL540124 | 0.75 | TSHR (0.36) | — | |
| SCHEMBL17239147 | 0.73 | TSHR (0.35) | — | |
| SCHEMBL28490351 | 0.71 | TSHR (0.33) | — | |
| SCHEMBL3893657 | 0.69 | TSHR (0.32) | — | |
| SCHEMBL17239065 | 0.69 | — | — | |
| SCHEMBL4443775 | 0.65 | TSHR (0.53) | — | |
| SCHEMBL441930 | 0.65 | — | — | |
| SCHEMBL13564174 | 0.65 | — | — | |
| SCHEMBL674291 | 0.65 | — | — | |
| SCHEMBL5611152 | 0.64 | LMNA (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110021460-A1 | SELECTIVE HYDROSILYLATION METHOD AND PRODUCT | MOMENTIVE PERFORMANCE MATERIALS, INC. | 2011-01-27 | — | — | US | claimed |
| US-7834118-B2 | Selective hydrosilylation method with rhodium catalyst | MOMENTIVE PERFORMANCE MATERIALS INC (US) | 2010-11-16 | — | — | US | claimed |
| US-20080081924-A1 | SELECTIVE MOLAR EXCESS HYDROSILYLATION METHOD AND PRODUCT | MOMENTIVE PERFORMANCE MATERIALS INC. | 2008-04-03 | — | — | US | claimed |
| US-20080076896-A1 | SELECTIVE HYDROSILYLATION METHOD AND PRODUCT | MOMENTIVE PERFORMANCE MATERIALS INC. | 2008-03-27 | — | — | US | claimed |
| US-20080076939-A1 | Two-step process of reacting a dihydroorganosiloxane with a terminally unsaturated compound in the presence of a rhodium catalyst and then with a different unsaturated compound to form an assymetrically disubstitued siloxane; one of the unsaturated compounds is an alkenyl polyalkylene oxide | MOMENTIVE PERFORMANCE MATERIALS INC. | 2008-03-27 | — | — | US | claimed |
| US-7326761-B1 | Selective hydrosilylation method and product | GENERAL ELECTRIC COMPANY (US) | 2008-02-05 | — | — | US | claimed |
| US-20080015325-A1 | SELECTIVE HYDROSILYLATION METHOD AND PRODUCT | MOMENTIVE PERFORMANCE MATERIALS INC. | 2008-01-17 | — | — | US | claimed |
| US-20080015323-A1 | SELECTIVE HYDROSILYLATION METHOD AND PRODUCT | MOMENTIVE PERFORMANCE MATERIALS INC. | 2008-01-17 | — | — | US | claimed |
| US-20080015324-A1 | Use of tris(dibutylsulfide)rhodium trichloride catalyst to make a siloxane-functional polyoxyalkylene glycol; use as a hydrolysis resistant-imparting agent for a composition in need of hydrolysis resistance such as agrochemical, personal care, and home care formulations | MOMENTIVE PERFORMANCE MATERIALS INC. | 2008-01-17 | — | — | US | claimed |
| US-7259220-B1 | Selective hydrosilylation method | GENERAL ELECTRIC COMPANY (US) | 2007-08-21 | — | — | US | claimed |
| US-8217129-B2 | Polyalkylene oxide asymmetric siloxane | MOMENTIVE PERFORMANCE MATERIALS (US) | 2012-07-10 | — | — | US | disclosed |
| US-20120035385-A1 | SELECTING CATALYST AND CONDITIONS | RINARD CHAUNCEY J (US) | 2012-02-09 | — | — | US | disclosed |
| US-20110172453-A1 | ASYMMETRIC SILOXANE | MOMENTIVE PERFORMANCE MATERIALS INC. | 2011-07-14 | — | — | US | disclosed |
| US-7968666-B2 | Use of rhodium catalyst to make a siloxane-functional polyoxyalkylene glycol; use as a hydrolysis resistant-imparting agent for agrochemical, personal care, and home care formulations; tetramethyldisiloxane and vinyltrimethylsilane reaction product further reacted with allyloxy-methoxypolyethylene glycol | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2011-06-28 | — | — | US | disclosed |
| US-7947798-B2 | Reacting a dihydridosiloxane with an olefin started alcohol with carbon to carbon double bond or with an olefin started epoxide, hydrosilylating with a second and different hydrocarbon with a carbon double bond, forming an asymmetrically substituted organosiloxane | MOMENTIVE PERFORMANCE MATERIALS INC. | 2011-05-24 | — | — | US | disclosed |
| US-6652608-B1 | Fuel compositions exhibiting improved fuel stability | OCTANE INTERNATIONAL, LTD. | 2003-11-25 | — | — | US | disclosed |
| EP-1051461-A2 | FUEL COMPOSITIONS EMPLOYING CATALYST COMBUSTION STRUCTURE | ORR, William C. (US) | 2000-11-15 | — | — | EP | disclosed |
| WO-1999066009-A2 | FUEL COMPOSITIONS EMPLOYING CATALYST COMBUSTION STRUCTURE | ORR WILLIAM C (US) | 1999-12-23 | — | — | WO | disclosed |
| EP-0954558-A1 | FUEL COMPOSITIONS EXHIBITING IMPROVED FUEL STABILITY | ORR, William C. (US) | 1999-11-10 | — | — | EP | disclosed |
| WO-1998026028-A1 | FUEL COMPOSITIONS EXHIBITING IMPROVED FUEL STABILITY | ORR WILLIAM C (US) | 1998-06-18 | — | — | WO | disclosed |