Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 3/20 | 0.71 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.59 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6047213 | 0.87 | ADORA2A (0.82) | ADORA2A | |
| SCHEMBL12612295 | 0.86 | ADORA2A (0.68) | ADORA2AADORA2BADORA1 | |
| SCHEMBL19596873 | 0.86 | ADORA2A (0.68) | ADORA2A | |
| SCHEMBL3541623 | 0.86 | ADORA2A (0.68) | ADORA2AADORA2BADORA1 | |
| SCHEMBL6047334 | 0.83 | ADORA2A (1.00) | ADORA2A | |
| SCHEMBL6047223 | 0.82 | ADORA2A (0.64) | ADORA2AADORA2BADORA1 | |
| SCHEMBL6047272 | 0.82 | ADORA2A (0.64) | ADORA2A | |
| SCHEMBL3548138 | 0.82 | ADORA2A (0.63) | ADORA2AADORA2BADORA1 | |
| SCHEMBL6047175 | 0.81 | ADORA2A (0.66) | ADORA2A | |
| SCHEMBL6047331 | 0.81 | ADORA2A (0.81) | ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070010522-A1 | Triazolo[1,5-c]pyrimidines and pyrazolo[1,5-c]pyrimidines useful as a2a adenosine receptor antagonists | BIOGEN IDEC MA INC. | 2007-01-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070010522-A1 | Triazolo[1,5-c]pyrimidines and pyrazolo[1,5-c]pyrimidines useful as a2a adenosine receptor antagonists | ADORA2A, ADORA3, ADORA1 | ADORA2A 1/4885ADORA2B 4/4885ADORA1 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.