Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP9 | P14780 | 11/20 | 0.74 |
| ▸ | MMP2 | P08253 | 10/20 | 0.74 |
| ▸ | MMP1 | P03956 | 4/20 | 0.68 |
| ▸ | MMP13 | P45452 | 4/20 | 0.68 |
| ▸ | MMP3 | P08254 | 3/20 | 0.68 |
| ▸ | MMP7 | P09237 | 3/20 | 0.68 |
| ▸ | MMP14 | P50281 | 4/20 | 0.59 |
| ▸ | ADAM10 | O14672 | 3/20 | 0.59 |
| ▸ | ADAM17 | P78536 | 3/20 | 0.59 |
| ▸ | PTGER4 | P35408 | 3/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.53 |
| ▸ | MMP8 | P22894 | 3/20 | 0.49 |
| ▸ | MMP12 | P39900 | 2/20 | 0.49 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.49 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5653366 | 0.83 | PTGER4 (0.69) | MMP9MMP2PTGER4HTTFOLH1 | |
| SCHEMBL23574915 | 0.80 | PTGER4 (0.70) | PTGER4HTTFOLH1SIRT5 | |
| SCHEMBL22750161 | 0.80 | PTGER4 (0.70) | PTGER4HTTFOLH1SIRT5 | |
| SCHEMBL6122901 | 0.80 | MMP2 (0.90) | MMP9MMP2MMP1MMP13MMP3 | |
| SCHEMBL5653457 | 0.80 | PTGER4 (0.73) | PTGER4HTTFOLH1SIRT5CA1 | |
| SCHEMBL5656638 | 0.79 | MMP2 (0.56) | MMP9MMP2MMP1MMP13MMP3 | |
| SCHEMBL15238617 | 0.78 | MMP2 (0.76) | MMP9MMP2MMP1MMP13MMP3 | |
| SCHEMBL2876850 | 0.78 | HTT (0.88) | PTGER4HTTFOLH1 | |
| SCHEMBL4858734 | 0.78 | HTT (0.88) | PTGER4HTTFOLH1 | |
| SCHEMBL4857273 | 0.78 | HTT (0.88) | PTGER4HTTFOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070142638-A1 | Ornithine derivatives as prostaglandin e2 agonists or antagonists | ASTELLAS PHARMA INC. (JP) | 2007-06-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070142638-A1 | Ornithine derivatives as prostaglandin e2 agonists or antagonists | PTGER4, OXER1, RXFP4 | MMP9 4006/4885MMP2 3589/4885MMP1 4205/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.