Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | TBXAS1 | P24557 | 3/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 2/20 | 0.40 |
| ▸ | PPARA | Q07869 | 2/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.39 |
| ▸ | EPAS1 | Q99814 | 2/20 | 0.39 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.39 |
| ▸ | KDM4A | O75164 | 1/20 | 0.39 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.39 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5654022 | 1.00 | PTPN1 (0.45) | PTPN1ALDH1A1MAPTTBXAS1KDM1A | |
| SCHEMBL9751222 | 1.00 | PTPN1 (0.45) | PTPN1ALDH1A1MAPTTBXAS1KDM1A | |
| SCHEMBL1740084 | 1.00 | PTPN1 (0.45) | PTPN1ALDH1A1MAPTTBXAS1KDM1A | |
| SCHEMBL23924669 | 1.00 | PTPN1 (0.45) | PTPN1ALDH1A1MAPTTBXAS1KDM1A | |
| SCHEMBL22555602 | 1.00 | PTPN1 (0.45) | PTPN1ALDH1A1MAPTTBXAS1KDM1A | |
| SCHEMBL23924379 | 1.00 | PTPN1 (0.45) | PTPN1ALDH1A1MAPTTBXAS1KDM1A | |
| SCHEMBL5654028 | 1.00 | PTPN1 (0.45) | PTPN1ALDH1A1MAPTTBXAS1KDM1A | |
| SCHEMBL9751266 | 1.00 | PTPN1 (0.45) | PTPN1ALDH1A1MAPTTBXAS1KDM1A | |
| SCHEMBL301125 | 1.00 | PTPN1 (0.45) | PTPN1ALDH1A1MAPTTBXAS1KDM1A | |
| SCHEMBL1470934 | 1.00 | PTPN1 (0.45) | PTPN1ALDH1A1MAPTTBXAS1KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1259470-A4 | A GROUP OF ANTI-CANCER COMPOUNDS WITH SPECIFIC STRUCTURE AND THEIR PRODUCTION METHOD | YANG ZHENHUA (US) | 2005-06-15 | — | — | EP | claimed |
| US-20040034242-A1 | Group of anti-cancer compounds with specific structure and their production method | YANG ZHENHUA (US) | 2004-02-19 | — | — | US | claimed |
| EP-1259470-A2 | A GROUP OF ANTI-CANCER COMPOUNDS WITH SPECIFIC STRUCTURE AND THEIR PRODUCTION METHOD | Yang, Zhenhua (US) | 2002-11-27 | — | — | EP | claimed |
| WO-2001059067-A2 | A GROUP OF ANTI-CANCER COMPOUNDS WITH SPECIFIC STRUCTURE AND THEIR PRODUCTION METHOD | YANG ZHENHUA (US) | 2001-08-16 | — | — | WO | claimed |
| CN-113527420-A | Antibacterial calcium-dependent antibiotic (CDA) analogs and methods of treating bacterial infections | 香港大学 | 2021-10-22 | — | — | CN | disclosed |
| US-20210324009-A1 | ANTI-BACTERIAL CALCIUM-DEPENDENT ANTIBIOTIC (CDA) ANALOGS AND METHODS OF TREATING BACTERIAL INFECTIONS | THE UNIVERSITY OF HONG KONG (CN) | 2021-10-21 | — | — | US | disclosed |
| EP-1309336-B1 | DERIVATIVES OF LASPARTOMYCIN AND PREPARATION AND USE THEREOF | BIOSOURCE PHARM INC (US) | 2009-05-06 | — | — | EP | disclosed |
| US-7109364-B2 | Group of anti-cancer compounds with specific structure and their production method | YANG ZHENHUA | 2006-09-19 | — | — | US | disclosed |
| EP-1259470-A4 | A GROUP OF ANTI-CANCER COMPOUNDS WITH SPECIFIC STRUCTURE AND THEIR PRODUCTION METHOD | YANG ZHENHUA (US) | 2005-06-15 | — | — | EP | disclosed |
| US-20040034242-A1 | Group of anti-cancer compounds with specific structure and their production method | YANG ZHENHUA (US) | 2004-02-19 | — | — | US | disclosed |
| EP-1259470-A2 | A GROUP OF ANTI-CANCER COMPOUNDS WITH SPECIFIC STRUCTURE AND THEIR PRODUCTION METHOD | Yang, Zhenhua (US) | 2002-11-27 | — | — | EP | disclosed |
| WO-2001059067-A2 | A GROUP OF ANTI-CANCER COMPOUNDS WITH SPECIFIC STRUCTURE AND THEIR PRODUCTION METHOD | YANG ZHENHUA (US) | 2001-08-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210324009-A1 | ANTI-BACTERIAL CALCIUM-DEPENDENT ANTIBIOTIC (CDA) ANALOGS AND METHODS OF TREATING BACTERIAL INFECTIONS | ORAI1, CASR, CALCA | PTPN1 1766/4885ALDH1A1 4437/4885MAPT 2933/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.