Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 4/20 | 0.65 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.46 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.46 |
| ▸ | SIRT5 | Q9NXA8 | 5/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | SIRT2 | Q8IXJ6 | 7/20 | 0.44 |
| ▸ | SIRT1 | Q96EB6 | 6/20 | 0.44 |
| ▸ | SIRT3 | Q9NTG7 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5652303 | 0.93 | PTGER4 (0.63) | PTGER4HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL5653855 | 0.92 | PTGER4 (0.65) | PTGER4HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL5797447 | 0.91 | PTGER4 (0.71) | PTGER4HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL5797231 | 0.90 | PTGER4 (0.77) | PTGER4SIRT5NPC1TP53RAB9A | |
| SCHEMBL5654913 | 0.89 | PTGER4 (0.67) | PTGER4HDAC1SIRT5NPC1TP53 | |
| SCHEMBL5657013 | 0.89 | PTGER4 (0.65) | PTGER4HDAC4HDAC1HDAC2HDAC6 | |
| SCHEMBL5653676 | 0.88 | PTGER4 (0.64) | PTGER4HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL5653440 | 0.87 | PTGER4 (0.63) | PTGER4HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL5654420 | 0.86 | PTGER4 (0.74) | PTGER4SMN1; SMN2 | |
| SCHEMBL5737965 | 0.85 | PTGER4 (0.70) | PTGER4HDAC3HDAC4HDAC1HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070142638-A1 | Ornithine derivatives as prostaglandin e2 agonists or antagonists | ASTELLAS PHARMA INC. (JP) | 2007-06-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070142638-A1 | Ornithine derivatives as prostaglandin e2 agonists or antagonists | PTGER4, OXER1, RXFP4 | PTGER4 1/4885HDAC3 1179/4885HDAC4 401/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.