SCHEMBL5654580

SCHEMBL5654580

CCO[Si](CCCSCC)(OCC)OCC

nearest known ligand 0.35

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.35
ALDH1A1 P00352 1/20 0.32
CYP3A4 P08684 1/20 0.32
HSD17B10 Q99714 1/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
TDP1 Q9NUW8 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL83049 0.91
SCHEMBL29420349 0.88
SCHEMBL29107205 0.88
SCHEMBL1842205 0.88
SCHEMBL29420367 0.88
SCHEMBL29420375 0.88
SCHEMBL29420382 0.86
SCHEMBL29420333 0.86
SCHEMBL29420358 0.86
SCHEMBL22777449 0.84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112513055-B Thioether silanes, process for their production and their use 赢创运营有限公司 2024-06-25 CN disclosed
EP-3830095-B1 THIOETHER SILANES, METHOD FOR THE PRODUCTION THEREOF, AND USE THEREOF EVONIK OPERATIONS GMBH (DE) 2022-09-07 EP disclosed
US-20210292514-A1 THIOETHER SILANES, METHOD FOR THE PRODUCTION THEREOF, AND USE THEREOF EVONIK OPERATIONS GMBH (DE) 2021-09-23 US disclosed
EP-3830095-A1 THIOETHER SILANES, METHOD FOR THE PRODUCTION THEREOF, AND USE THEREOF Evonik Operations GmbH (DE) 2021-06-09 EP disclosed
WO-2020025309-A1 THIOETHER SILANES, METHOD FOR THE PRODUCTION THEREOF, AND USE THEREOF EVONIK OPERATIONS GMBH (DE) 2020-02-06 WO disclosed
US-7301042-B2 Blocked mercaptosilane hydrolyzates as coupling agents for mineral-filled elastomer compositions MOMENTIVE PERFORMANCE MATERIALS INC. 2007-11-27 US disclosed
EP-1529073-A1 BLOCKED MERCAPTOSILANE HYDROLYZATES AS COUPLING AGENTS FOR MINERAL-FILLED ELASTOMER COMPOSITIONS GENERAL ELECTRIC COMPANY (US) 2005-05-11 EP disclosed
WO-2003091314-A1 BLOCKED MERCAPTOSILANE HYDROLYZATES AS COUPLING AGENTS FOR MINERAL-FILLED ELASTOMER COMPOSITIONS GENERAL ELECTRIC COMPANY (US) 2003-11-06 WO disclosed
US-20030199619-A1 Blocked mercaptosilane hydrolyzates as coupling agents for mineral-filled elastomer compositions CROMPTON CORPORATION 2003-10-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210292514-A1 THIOETHER SILANES, METHOD FOR THE PRODUCTION THEREOF, AND USE THEREOF CBR3, TST, GLRX3 TSHR 156/4885ALDH1A1 2888/4885CYP3A4 325/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.