Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 4/20 | 0.65 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | SIRT2 | Q8IXJ6 | 9/20 | 0.44 |
| ▸ | SIRT1 | Q96EB6 | 9/20 | 0.44 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.44 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.44 |
| ▸ | SIRT3 | Q9NTG7 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.43 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5654913 | 0.93 | PTGER4 (0.67) | PTGER4NPC1RAB9ACA1CA2 | |
| SCHEMBL5653676 | 0.90 | PTGER4 (0.64) | PTGER4MEN1KMT2ANPC1RAB9A | |
| SCHEMBL5653440 | 0.90 | PTGER4 (0.63) | PTGER4MEN1KMT2ANPC1RAB9A | |
| SCHEMBL5652303 | 0.90 | PTGER4 (0.63) | PTGER4MEN1KMT2ANPC1RAB9A | |
| SCHEMBL5797231 | 0.87 | PTGER4 (0.77) | PTGER4NPC1RAB9ASIRT2SIRT1 | |
| SCHEMBL5653684 | 0.85 | PTGER4 (0.72) | PTGER4CA1CA2TAS1R3TAS1R1 | |
| SCHEMBL5654459 | 0.85 | PTGER4 (0.63) | PTGER4MEN1KMT2ANPC1RAB9A | |
| SCHEMBL5797447 | 0.85 | PTGER4 (0.71) | PTGER4SIRT2SIRT1SIRT3 | |
| SCHEMBL5653187 | 0.85 | PTGER4 (0.71) | PTGER4MEN1KMT2ANPC1RAB9A | |
| SCHEMBL5737965 | 0.84 | PTGER4 (0.70) | PTGER4SIRT2SIRT1SIRT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070142638-A1 | Ornithine derivatives as prostaglandin e2 agonists or antagonists | ASTELLAS PHARMA INC. (JP) | 2007-06-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070142638-A1 | Ornithine derivatives as prostaglandin e2 agonists or antagonists | PTGER4, OXER1, RXFP4 | PTGER4 1/4885MEN1 4001/4885KMT2A 1128/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.