Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 1.00 |
| ▸ | GFER | P55789 | 4/20 | 1.00 |
| ▸ | GAA | P10253 | 4/20 | 1.00 |
| ▸ | ADRA2C | P18825 | 2/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 2/20 | 1.00 |
| ▸ | PTK2B | Q14289 | 2/20 | 1.00 |
| ▸ | ESR2 | Q92731 | 1/20 | 1.00 |
| ▸ | LMNA | P02545 | 4/20 | 0.63 |
| ▸ | HTT | P42858 | 3/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.62 |
| ▸ | RAD52 | P43351 | 2/20 | 0.62 |
| ▸ | RECQL | P46063 | 2/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | NPC1 | O15118 | 1/20 | 0.59 |
| ▸ | USP2 | O75604 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6151538 | 1.00 | MAPT (1.00) | MAPTKDM4EALDH1A1GFERGAA | |
| SCHEMBL6414948 | 1.00 | MAPT (1.00) | MAPTKDM4EALDH1A1GFERGAA | |
| Hydrochloric Acid SCHEMBL3271552 | 0.98 | MAPT (0.96) | MAPTKDM4EALDH1A1GFERGAA | |
| Hydrochloric Acid SCHEMBL4707631 | 0.98 | MAPT (0.96) | MAPTKDM4EALDH1A1GFERGAA | |
| SCHEMBL25894824 | 0.94 | MAPT (0.88) | MAPTKDM4EALDH1A1GFERGAA | |
| SCHEMBL217159 | 0.92 | MAPT (0.85) | MAPTKDM4EALDH1A1GFERGAA | |
| Hydrochloric Acid SCHEMBL5203720 | 0.90 | MAPT (0.81) | MAPTKDM4EALDH1A1GFERGAA | |
| SCHEMBL23347931 | 0.88 | MAPT (0.77) | MAPTKDM4EALDH1A1GFERGAA | |
| SCHEMBL6151120 | 0.88 | MAPT (0.77) | MAPTKDM4EALDH1A1GFERGAA | |
| SCHEMBL7043679 | 0.88 | MAPT (0.77) | MAPTKDM4EALDH1A1GFERGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 2295 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122011344-A | Photo-thermal stable PTAA copolymer and preparation method thereof | 链行走新材料科技(广州)有限公司 | 2026-05-12 | — | — | CN | claimed |
| EP-4531856-B1 | BRUTON'S KINASE INHIBITORS FOR THE TREATMENT OF A SUDDEN ALLERGIC REACTION | ALK ABELLO AS (DK) | 2026-04-22 | — | — | EP | claimed |
| CN-119552131-A | Hyperbranched polyamide containing methylpiperazine and polytrianiline structures, and preparation method and application thereof | 黑龙江大学 | 2025-03-04 | — | — | CN | claimed |
| CN-119285624-A | Pyrimidine compound containing thiophene, preparation method thereof and application of pyrimidine compound in preparation of medicines with anticancer effect | 南方医科大学中西医结合医院 | 2025-01-10 | — | — | CN | claimed |
| CN-119264116-A | CDK6/9 dual inhibitor and preparation method and application thereof | 安徽中医药大学 | 2025-01-07 | — | — | CN | claimed |
| CN-115108931-B | Tofenamic acid derivative and preparation and application thereof | 南华大学附属第一医院 | 2024-06-14 | — | — | CN | claimed |
| CN-117820239-A | Novel CSF1R inhibitor and preparation method and application thereof | 四川大学华西医院 | 2024-04-05 | — | — | CN | claimed |
| CN-116768862-A | Indole pyrazole compound as well as preparation method and application thereof | 郑州大学 | 2023-09-19 | — | — | CN | claimed |
| CN-114805369-A | 2, 6-disubstituted purine compound and preparation method and application thereof | 自贡市第四人民医院(自贡市急救中心) | 2022-07-29 | — | — | CN | claimed |
| CN-114380822-A | CDKs inhibitor of beta-carboline mother nucleus, preparation method and anti-tumor application thereof | 中国人民解放军北部战区总医院 | 2022-04-22 | — | — | CN | claimed |
| US-20130131058-A1 | 2-SUBSTITUTED-8-ALKYL-7-OXO-7,8-DIHYDROPYRIDO[2,3-D] PYRIMIDINE-6-CARBONITRILES AND USES THEREOF | TEMPLE UNIVERSITY - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION | 2013-05-23 | — | — | US | claimed |
| WO-2012030160-A2 | QUINOLINE OR QUINAZOLINE DERIVATIVES WITH APOPTOSIS INDUCING ACTIVITY ON CELLS | HANMI HOLDINGS CO., LTD. (KR) | 2012-03-08 | — | — | WO | claimed |
| WO-2012018540-A1 | 2-SUBSTITUTED-8-ALKYL-7-OXO-7,8-DIHYDROPYRIDO[2,3-D] PYRIMIDINE-6-CARBONITRILES AND USES THEREOF | TEMPLE UNIVERSITY - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2012-02-09 | — | — | WO | claimed |
| CN-102238950-A | Certain kynurenine-3-monooxygenase inhibitors, pharmaceutical compositions, and methods of use | CHDI INC (US) | 2011-11-09 | — | — | CN | claimed |
| EP-2376491-A1 | PYRROLOTRIAZINES AS ALK AND JAK2 INHIBITORS | Cephalon, Inc. (US) | 2011-10-19 | — | — | EP | claimed |
| EP-2190834-B1 | PYRIDONEAMIDE DERIVATIVES AS FOCAL ADHESION KINASE (FAK) INHIBITORS AND THEIR USE FOR THE TREATMENT OF CANCER | HOFFMANN LA ROCHE (CH) | 2011-03-02 | — | — | EP | claimed |
| EP-2065380-A1 | Pyridoneamide derivatives as focal adhesion kinase (FAK) inhibitors and their use for the treatment of cancer | F.HOFFMANN-LA ROCHE AG (CH) | 2009-06-03 | — | — | EP | claimed |
| WO-2007097697-A1 | THERAPEUTIC QUINOLINE COMPOUNDS THAT ARE 5HT1B MODULATORS | ASTRAZENECA AB (SE) | 2007-08-30 | — | — | WO | claimed |
| WO-2003047575-A1 | THERAPEUTIC BENZAMIDE DERIVATIVES | GLAXO GROUP LIMITED (GB) | 2003-06-12 | — | — | WO | claimed |
| WO-2003048121-A1 | THERAPEUTIC BENZAMIDE DERIVATIVES | GLAXO GROUP LIMITED (GB) | 2003-06-12 | — | — | WO | claimed |