SCHEMBL23347931

SCHEMBL23347931

Nc1ccc(N2CC2)cc1

nearest known ligand 0.77

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 10/20 0.77
ALDH1A1 P00352 7/20 0.77
GFER P55789 6/20 0.77
LMNA P02545 6/20 0.77
GAA P10253 5/20 0.77
ADRA2C P18825 4/20 0.77
KDM4E B2RXH2 3/20 0.77
KMT2A Q03164 3/20 0.77
HTT P42858 2/20 0.77
MAPK1 P28482 2/20 0.77
TDP1 Q9NUW8 2/20 0.77
PTK2B Q14289 1/20 0.77
ESR2 Q92731 1/20 0.77
L3MBTL1 Q9Y468 2/20 0.73
MEN1 O00255 2/20 0.73
NPC1 O15118 1/20 0.73
USP2 O75604 1/20 0.73
TP53 P04637 1/20 0.73
POLB P06746 1/20 0.73
THRB P10828 1/20 0.73

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6151120 1.00 MAPT (0.77) MAPTALDH1A1GFERLMNAGAA
SCHEMBL7043679 1.00 MAPT (0.77) MAPTALDH1A1GFERLMNAGAA
SCHEMBL112440 0.92 MAPT (0.78) MAPTALDH1A1GFERLMNAGAA
SCHEMBL12952701 0.90 MAPT (0.65) MAPTALDH1A1GFERLMNAGAA
Hydrochloric Acid SCHEMBL5169602 0.90 MAPT (0.83) MAPTALDH1A1GFERLMNAGAA
SCHEMBL1858354 0.89 ALDH1A1 (0.82) MAPTALDH1A1GFERLMNAGAA
SCHEMBL33852 0.89 ALDH1A1 (0.91) MAPTALDH1A1GFERLMNAGAA
SCHEMBL3055201 0.88 MAPT (0.63) MAPTALDH1A1GFERLMNAGAA
SCHEMBL13159173 0.88 MAPT (0.63) MAPTALDH1A1GFERLMNAGAA
SCHEMBL6414948 0.88 MAPT (1.00) MAPTALDH1A1GFERLMNAGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118978525-A Light-activated labeled RNA photosensitizer based on phenothiazine, and preparation method and application thereof 大连理工大学宁波研究院 2024-11-19 CN claimed
EP-3535436-B1 PRECURSORS AND FLOWABLE CVD METHODS FOR MAKING LOW-K FILMS TO FILL SURFACE FEATURES VERSUM MAT US LLC (US) 2021-05-12 EP disclosed