Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 3/20 | 0.53 |
| ▸ | MMP9 | P14780 | 3/20 | 0.53 |
| ▸ | TLR2 | O60603 | 1/20 | 0.52 |
| ▸ | PTGER4 | P35408 | 3/20 | 0.51 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.51 |
| ▸ | CPB1 | P15086 | 1/20 | 0.50 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.50 |
| ▸ | MMP1 | P03956 | 1/20 | 0.49 |
| ▸ | MMP3 | P08254 | 1/20 | 0.49 |
| ▸ | MMP7 | P09237 | 1/20 | 0.49 |
| ▸ | MMP13 | P45452 | 1/20 | 0.49 |
| ▸ | SIRT2 | Q8IXJ6 | 6/20 | 0.49 |
| ▸ | SIRT1 | Q96EB6 | 4/20 | 0.49 |
| ▸ | SIRT3 | Q9NTG7 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5656638 | 0.90 | MMP2 (0.56) | MMP2MMP9TLR2PTGER4FOLH1 | |
| SCHEMBL5656118 | 0.86 | PTGER4 (0.59) | MMP2MMP9PTGER4FOLH1CPB1 | |
| SCHEMBL5656235 | 0.84 | MMP2 (0.47) | MMP2MMP9FOLH1CPB1CPB2 | |
| SCHEMBL5653166 | 0.83 | PTGER4 (0.62) | PTGER4FOLH1CPB1CPB2SIRT2 | |
| SCHEMBL5654338 | 0.82 | PTGER4 (0.56) | PTGER4FOLH1CPB1CPB2SIRT2 | |
| SCHEMBL3065465 | 0.82 | HTT (0.68) | FOLH1SIRT2SIRT1SIRT3 | |
| SCHEMBL131437 | 0.82 | HTT (0.68) | FOLH1SIRT2SIRT1SIRT3 | |
| SCHEMBL5651760 | 0.81 | MAPT (0.57) | PTGER4SIRT2SIRT1SIRT3MEN1 | |
| Hydrochloric Acid SCHEMBL5654724 | 0.81 | ANPEP (0.57) | PTGER4FOLH1SIRT2SIRT1SIRT3 | |
| SCHEMBL23223918 | 0.81 | HTT (0.69) | FOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070142638-A1 | Ornithine derivatives as prostaglandin e2 agonists or antagonists | ASTELLAS PHARMA INC. (JP) | 2007-06-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070142638-A1 | Ornithine derivatives as prostaglandin e2 agonists or antagonists | PTGER4, OXER1, RXFP4 | MMP2 3589/4885MMP9 4006/4885TLR2 778/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.