Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 4/20 | 0.77 |
| ▸ | FOLH1 | Q04609 | 3/20 | 0.57 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.54 |
| ▸ | ITGAV | P06756 | 2/20 | 0.54 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.52 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.52 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.52 |
| ▸ | MAOB | P27338 | 1/20 | 0.51 |
| ▸ | CPB1 | P15086 | 1/20 | 0.51 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | MMP2 | P08253 | 1/20 | 0.49 |
| ▸ | MMP9 | P14780 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5797231 | 0.90 | PTGER4 (0.77) | PTGER4NPC1RAB9ATP53SMN1; SMN2 | |
| SCHEMBL5653780 | 0.90 | PTGER4 (0.82) | PTGER4FOLH1TAS1R3TAS1R1CPB1 | |
| SCHEMBL5653232 | 0.89 | PTGER4 (0.93) | PTGER4FOLH1TAS1R3TAS1R1CPB1 | |
| SCHEMBL5653516 | 0.88 | PTGER4 (0.98) | PTGER4FOLH1CPB1CPB2CA1 | |
| SCHEMBL5653172 | 0.87 | PTGER4 (1.00) | PTGER4FOLH1CPB1CPB2 | |
| SCHEMBL5651834 | 0.87 | PTGER4 (1.00) | PTGER4FOLH1CPB1CPB2 | |
| SCHEMBL5797447 | 0.86 | PTGER4 (0.71) | PTGER4 | |
| SCHEMBL5653729 | 0.85 | PTGER4 (1.00) | PTGER4FOLH1CPB1CPB2 | |
| SCHEMBL5654536 | 0.85 | PTGER4 (1.00) | PTGER4FOLH1CPB1CPB2 | |
| SCHEMBL5655171 | 0.85 | PTGER4 (0.75) | PTGER4TAS1R3TAS1R1CPB1CPB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070142638-A1 | Ornithine derivatives as prostaglandin e2 agonists or antagonists | ASTELLAS PHARMA INC. (JP) | 2007-06-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070142638-A1 | Ornithine derivatives as prostaglandin e2 agonists or antagonists | PTGER4, OXER1, RXFP4 | PTGER4 1/4885FOLH1 2951/4885ITGB3 4270/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.