Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | GLA | P06280 | 1/20 | 0.52 |
| ▸ | PRSS12 | P56730 | 1/20 | 0.51 |
| ▸ | RHEB | Q15382 | 1/20 | 0.50 |
| ▸ | EZH2 | Q15910 | 7/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | LCK | P06239 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5654922 | 0.96 | MEN1 (0.61) | MEN1KMT2AGLAPRSS12RHEB | |
| SCHEMBL5653127 | 0.93 | RHEB (0.58) | MEN1KMT2AGLAPRSS12RHEB | |
| SCHEMBL5649925 | 0.90 | MEN1 (0.52) | MEN1KMT2AGLAPRSS12RHEB | |
| SCHEMBL5649916 | 0.88 | MEN1 (0.52) | MEN1KMT2AGLAPRSS12RHEB | |
| SCHEMBL5653226 | 0.86 | MEN1 (0.58) | MEN1KMT2AGLAEZH2POLB | |
| SCHEMBL5651443 | 0.86 | EZH2 (0.57) | MEN1KMT2AGLAEZH2POLB | |
| SCHEMBL5654366 | 0.84 | MEN1 (0.60) | MEN1KMT2AGLAPRSS12RHEB | |
| SCHEMBL5653216 | 0.83 | MEN1 (0.58) | MEN1KMT2AGLAEZH2POLB | |
| SCHEMBL5654931 | 0.82 | RHEB (0.56) | PRSS12RHEB | |
| SCHEMBL5654568 | 0.81 | MEN1 (0.56) | MEN1KMT2AGLAEZH2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7220769-B2 | Azolylbenzamides and analogues and their use for treating osteoporosis | NIKEM RESEARCH S.R.L. (IT) | 2007-05-22 | — | — | US | disclosed |
| US-20050038095-A1 | Azolylbenzamides and analogues and their use for treating osteoporosis | 3-V BIOSCIENCES, INC. | 2005-02-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050038095-A1 | Azolylbenzamides and analogues and their use for treating osteoporosis | NR0B2, NR0B1, NCOR1 | MEN1 3545/4885KMT2A 439/4885GLA 1633/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.