SCHEMBL5654956

SCHEMBL5654956

O=C(Oc1ccccc1)c1ccc(C(=O)O)c(OC(O)CO)c1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.44
ESR2 Q92731 1/20 0.44
ALDH1A1 P00352 8/20 0.43
MAPT P10636 6/20 0.43
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
NSD2 O96028 1/20 0.41
ALOX5 P09917 1/20 0.41
KDM4E B2RXH2 3/20 0.39
HPGD P15428 2/20 0.39
GAA P10253 2/20 0.39
GLA P06280 1/20 0.39
ATM Q13315 1/20 0.39
PARP10 Q53GL7 1/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
LMNA P02545 2/20 0.38
TP53 P04637 1/20 0.38
CYP3A4 P08684 1/20 0.38
ADORA3 P0DMS8 1/20 0.38
CHRM1 P11229 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7772665 0.78 MAPT (0.51) ALDH1A1MAPTKMT2AKDM4EHPGD
SCHEMBL9139507 0.76 KDM4E (0.50) ESR1ALDH1A1MAPTMEN1KMT2A
SCHEMBL11370233 0.76 HSD17B10 (0.58) ESR1ESR2ALDH1A1MAPTMEN1
SCHEMBL11733242 0.74 MAPT (0.54) ESR1ESR2ALDH1A1MAPTMEN1
SCHEMBL8752127 0.72 MAPT (0.51) ALDH1A1MAPTMEN1KMT2ANSD2
SCHEMBL347341 0.71 MAPT (0.57) ALDH1A1MAPTMEN1KMT2ANSD2
Phthalic Acid SCHEMBL10802155 0.70 PARP10 (0.59) ALDH1A1MAPTMEN1KMT2ANSD2
Benzoic Acid SCHEMBL28825753 0.70 DAO (0.50) ALDH1A1MEN1KMT2A
SCHEMBL11848517 0.69 HSD17B10 (0.52) ESR1ESR2ALDH1A1MAPTMEN1
SCHEMBL8459689 0.69 MAPT (0.51) ALDH1A1MAPTMEN1KMT2ANSD2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7303812-B2 Heat-shrinkable polyester films TOYO BOSEKI KABUSHIKI KAISHA (JP) 2007-12-04 US disclosed
EP-1340785-B1 Heat-shrinkable polyester films TOYO BOSEKI (JP) 2006-09-20 EP disclosed
US-20030165671-A1 Heat-shrinkable polyester films TOYO BOSEKI KABUSHIKI KAISHA (JP) 2003-09-04 US disclosed
EP-1340785-A2 Heat-shrinkable polyester films Toyo Boseki Kabushiki Kaisha (JP) 2003-09-03 EP disclosed
US-4945191-A CORE WIRE SURROUNDED BY DIELECTRIC LAYER OF CRYSTALLINE POLYESTER COPOLYMER, ALSO SHEATH; FOR TELEPHONES TOYO BOSEKI KABUSHIKI KAISHA (JP) 1990-07-31 US disclosed