SCHEMBL8459689

SCHEMBL8459689

O=C(Oc1ccccc1)c1ccc(C(=O)Oc2ccccc2)c(-c2ccccc2)c1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 7/20 0.51
ALDH1A1 P00352 4/20 0.51
TDP1 Q9NUW8 2/20 0.51
MEN1 O00255 1/20 0.50
KMT2A Q03164 1/20 0.50
NSD2 O96028 1/20 0.50
SMN1; SMN2 Q16637 2/20 0.49
LMNA P02545 1/20 0.49
TP53 P04637 1/20 0.49
CYP3A4 P08684 1/20 0.49
ADORA3 P0DMS8 1/20 0.49
CHRM1 P11229 1/20 0.49
TBXA2R P21731 1/20 0.49
SLC6A2 P23975 1/20 0.49
PDE4A P27815 1/20 0.49
ADRA1A P35348 1/20 0.49
KDR P35968 1/20 0.49
SLC6A3 Q01959 1/20 0.49
HDAC6 Q9UBN7 1/20 0.49
HPGD P15428 2/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phosphoric Acid SCHEMBL8462680 0.94 MAPT (0.47) MAPTALDH1A1TDP1MEN1KMT2A
SCHEMBL7916728 0.92 MAPT (0.48) MAPTALDH1A1TDP1NSD2SMN1; SMN2
SCHEMBL7584909 0.87 MAPT (0.51) MAPTALDH1A1TDP1MEN1KMT2A
SCHEMBL9152470 0.84 HPGD (0.53) MAPTALDH1A1TDP1MEN1KMT2A
SCHEMBL347341 0.83 MAPT (0.57) MAPTALDH1A1TDP1MEN1KMT2A
SCHEMBL9247710 0.83 MAPT (0.56) MAPTALDH1A1TDP1KMT2ANSD2
SCHEMBL8198688 0.83 HDAC7 (0.59) MAPTTDP1SMN1; SMN2LMNATP53
SCHEMBL7551787 0.82 HSD17B10 (0.54) MAPTALDH1A1TDP1MEN1KMT2A
SCHEMBL3453990 0.81 HSD17B10 (0.61) MAPTALDH1A1TDP1MEN1KMT2A
SCHEMBL11227264 0.81 PTK2B (0.48) MAPTALDH1A1MEN1KMT2ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1677194-A Method for evaluating polymer for liquid crystal directional agent and the directional agent thereof JSR CO LTD (JP) 2005-10-05 CN disclosed
US-5876851-A PROTECTIVE COATING ON METAL TEIJIN LIMITED (JP) 1999-03-02 US disclosed