Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 4/20 | 0.59 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.50 |
| ▸ | SIRT2 | Q8IXJ6 | 7/20 | 0.47 |
| ▸ | SIRT1 | Q96EB6 | 5/20 | 0.47 |
| ▸ | SIRT3 | Q9NTG7 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | CTSL | P07711 | 1/20 | 0.46 |
| ▸ | CTSS | P25774 | 1/20 | 0.46 |
| ▸ | CPB1 | P15086 | 1/20 | 0.46 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5652265 | 0.94 | PTGER4 (0.68) | PTGER4HDAC1HDAC2SIRT2SIRT1 | |
| SCHEMBL12193390 | 0.86 | PTGER4 (0.54) | PTGER4HDAC1HDAC2SIRT2SIRT1 | |
| SCHEMBL5653800 | 0.86 | PTGER4 (0.46) | PTGER4HDAC1HDAC2SIRT2SIRT1 | |
| SCHEMBL5653166 | 0.84 | PTGER4 (0.62) | PTGER4SIRT2SIRT1SIRT3MEN1 | |
| SCHEMBL5652490 | 0.84 | PTGER4 (0.48) | PTGER4HDAC1HDAC2CTSLCTSS | |
| SCHEMBL5653832 | 0.84 | PTGER4 (0.62) | PTGER4SIRT2SIRT1SIRT3MEN1 | |
| SCHEMBL5653073 | 0.83 | PTGER4 (0.49) | PTGER4HDAC1HDAC2CTSLCTSS | |
| SCHEMBL5653223 | 0.83 | PTGER4 (0.51) | PTGER4HDAC1HDAC2CTSLCTSS | |
| SCHEMBL5823969 | 0.82 | PTGER4 (0.47) | PTGER4SIRT2SIRT1SIRT3CTSL | |
| SCHEMBL5653738 | 0.82 | CTSS (0.47) | PTGER4SIRT2SIRT1SIRT3CTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070142638-A1 | Ornithine derivatives as prostaglandin e2 agonists or antagonists | ASTELLAS PHARMA INC. (JP) | 2007-06-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070142638-A1 | Ornithine derivatives as prostaglandin e2 agonists or antagonists | PTGER4, OXER1, RXFP4 | PTGER4 1/4885HDAC1 1416/4885HDAC2 815/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.