Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 20/20 | 0.56 |
| ▸ | MTOR | P42345 | 14/20 | 0.56 |
| ▸ | PIK3CD | O00329 | 13/20 | 0.56 |
| ▸ | PIK3CG | P48736 | 7/20 | 0.56 |
| ▸ | PIK3CB | P42338 | 6/20 | 0.56 |
| ▸ | PIK3C2A | O00443 | 2/20 | 0.47 |
| ▸ | PIK3C2B | O00750 | 2/20 | 0.47 |
| ▸ | PIK3C3 | Q8NEB9 | 2/20 | 0.47 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.47 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.47 |
| ▸ | CSF1R | P07333 | 1/20 | 0.47 |
| ▸ | MET | P08581 | 1/20 | 0.47 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.47 |
| ▸ | LTK | P29376 | 1/20 | 0.47 |
| ▸ | CDK7 | P50613 | 1/20 | 0.47 |
| ▸ | NEK2 | P51955 | 1/20 | 0.47 |
| ▸ | JAK3 | P52333 | 1/20 | 0.47 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.47 |
| ▸ | PRKDC | P78527 | 1/20 | 0.47 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31439371 | 0.86 | PIK3CD (0.71) | PIK3CAMTORPIK3CDPIK3CGPIK3CB | |
| SCHEMBL31439397 | 0.86 | PIK3CA (0.57) | PIK3CAMTORPIK3CDPIK3CGPIK3CB | |
| SCHEMBL31439347 | 0.85 | PIK3CA (0.53) | PIK3CAMTORPIK3CDPIK3CGPIK3CB | |
| SCHEMBL31439345 | 0.85 | PIK3CA (0.53) | PIK3CAMTORPIK3CDPIK3CGPIK3CB | |
| SCHEMBL31439336 | 0.84 | PIK3CA (0.52) | PIK3CAMTORPIK3CDPIK3CGPIK3CB | |
| SCHEMBL14873046 | 0.84 | PIK3CA (0.51) | PIK3CAMTORPIK3CDPIK3CGPIK3CB | |
| SCHEMBL27914183 | 0.84 | PIK3CA (0.54) | PIK3CAMTORPIK3CDPIK3CGPIK3CB | |
| SCHEMBL31439288 | 0.84 | PIK3CA (0.56) | PIK3CAMTORPIK3CDPIK3CGPIK3CB | |
| SCHEMBL31439293 | 0.84 | MTOR (0.49) | PIK3CAMTORPIK3CDPIK3CGPIK3CB | |
| SCHEMBL31439395 | 0.83 | PIK3CA (0.51) | PIK3CAMTORPIK3CDPIK3CGPIK3CB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119661531-A | Imidazolone compound as well as preparation method and application thereof | 北京富龙康泰生物技术有限公司 | 2025-03-21 | — | — | CN | disclosed |
| US-20070213355-A1 | 1H-Imidazo[4,5-C]Quinoline Derivatives in the Treatment of Protein Kinase Dependent Diseases | CAPRARO HANS-GEORG | 2007-09-13 | — | — | US | disclosed |
| EP-1689747-A1 | 1H-IMIDAZO [4,5-C] QUINOLINE DERIVATIVES IN THE TREATMENT OF PROTEIN KINASE DEPENDENT DISEASES | Novartis AG (CH) | 2006-08-16 | — | — | EP | disclosed |
| WO-2005054238-A1 | 1H-IMIDAZO[4,5-C]QUINOLINE DERIVATIVES IN THE TREATMENT OF PROTEIN KINASE DEPENDENT DISEASES | NOVARTIS AG (CH) | 2005-06-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070213355-A1 | 1H-Imidazo[4,5-C]Quinoline Derivatives in the Treatment of Protein Kinase Dependent Diseases | ABL1, PRKCA, PRKCQ | PIK3CA 466/4885MTOR 612/4885PIK3CD 304/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.