Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR3 | P49019 | 5/20 | 0.64 |
| ▸ | XDH | P47989 | 1/20 | 0.51 |
| ▸ | PLK1 | P53350 | 3/20 | 0.50 |
| ▸ | KDM5A | P29375 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | CISD1 | Q9NZ45 | 5/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15412946 | 0.85 | HCAR3 (0.64) | HCAR3XDHPLK1TP53TSHR | |
| SCHEMBL15412525 | 0.84 | HCAR3 (0.62) | HCAR3XDHPLK1TP53TSHR | |
| SCHEMBL15412739 | 0.84 | HCAR3 (0.62) | HCAR3XDHPLK1TP53TSHR | |
| SCHEMBL11255414 | 0.84 | HCAR3 (0.62) | HCAR3XDHPLK1TP53TSHR | |
| SCHEMBL11262794 | 0.83 | HCAR3 (0.61) | HCAR3XDHPLK1TP53TSHR | |
| SCHEMBL22499502 | 0.82 | CISD1 (0.60) | HCAR3XDHPLK1TSHRCISD1 | |
| SCHEMBL22499594 | 0.82 | CISD1 (0.60) | HCAR3XDHPLK1TSHRCISD1 | |
| SCHEMBL22097725 | 0.82 | HCAR3 (0.60) | HCAR3XDHPLK1CISD1 | |
| SCHEMBL15412506 | 0.82 | HCAR3 (0.60) | HCAR3XDHTP53TSHR | |
| SCHEMBL5915243 | 0.81 | HCAR3 (0.59) | HCAR3XDHTP53TSHRCISD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7071214-B2 | Compounds and compositions for delivering active agents | EMISPHERE TECHNOLOGIES, INC. (US) | 2006-07-04 | — | — | US | disclosed |