SCHEMBL5655445

SCHEMBL5655445

CCNS(=O)(=O)c1cccs1

nearest known ligand 0.72

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CYP2D6 P10635 1/20 0.72
CYP2C9 P11712 1/20 0.72
CYP2C19 P33261 1/20 0.72
TSHR P16473 2/20 0.55
HPGD P15428 1/20 0.55
L3MBTL1 Q9Y468 1/20 0.55
ALDH1A1 P00352 3/20 0.54
NPC1 O15118 1/20 0.54
RAB9A P51151 1/20 0.54
ATM Q13315 1/20 0.54
TP53 P04637 1/20 0.52
PKM P14618 1/20 0.51
LMNA P02545 1/20 0.51
RECQL P46063 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5652601 0.85 CYP2D6 (0.79) CYP2D6CYP2C9CYP2C19TSHRHPGD
SCHEMBL1164461 0.82 CYP2D6 (0.74) CYP2D6CYP2C9CYP2C19TSHRALDH1A1
SCHEMBL5512457 0.81 CYP2D6 (0.68) CYP2D6CYP2C9CYP2C19TSHRHPGD
SCHEMBL23052533 0.81 CYP2D6 (0.72) CYP2D6CYP2C9CYP2C19TSHRALDH1A1
SCHEMBL28588864 0.81 CYP2D6 (0.72) CYP2D6CYP2C9CYP2C19TSHRHPGD
SCHEMBL5200239 0.80 CYP2C9 (0.66) CYP2D6CYP2C9CYP2C19TSHRHPGD
SCHEMBL26242973 0.80 CYP2D6 (0.66) CYP2D6CYP2C9CYP2C19TSHRHPGD
SCHEMBL15009831 0.80 CYP2C9 (0.66) CYP2D6CYP2C9CYP2C19TSHRHPGD
SCHEMBL15018169 0.80 CYP2D6 (0.66) CYP2D6CYP2C9CYP2C19TSHRHPGD
SCHEMBL27601052 0.80 CYP2D6 (0.70) CYP2D6CYP2C9CYP2C19TSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119447465-A Electrolyte and application thereof in double-ion battery 广西师范大学 2025-02-14 CN claimed
CN-119447465-A Electrolyte and application thereof in double-ion battery 广西师范大学 2025-02-14 CN disclosed
WO-2023061051-A1 SULFAMIDE USP8 INHIBITOR AND USE THEREOF 中国药科大学 2023-04-20 WO disclosed
US-7943616-B2 Protein kinase inhibitors; astham; psoriasis; antiinflammatory agents; inflammatory bowel disorders AVENTIS PHARMACEUTICALS INC. (US) 2011-05-17 US disclosed
US-7687459-B2 Arylalkoxyl hepatitis C virus protease inhibitors ENANTA PHARMACEUTICALS, INC. (US) 2010-03-30 US disclosed
US-20090098085-A1 TETRAZOLYL ACYCLIC HEPATITIS C SERINE PROTEASE INHIBITORS ENANTA PHARMACEUTICALS, INC. 2009-04-16 US disclosed
US-7511063-B2 High affinity quinoline-based kinase ligands SCHERING CORPORATION (US) 2009-03-31 US disclosed
US-20090005387-A1 QUINOXALINYL MACROCYCLIC HEPATITIS C VIRUS SERINE PROTEASE INHIBITORS ENANTA PHARMACEUTICALS, INC. 2009-01-01 US disclosed
US-20080317712-A1 ARYLPIPERIDINYL AND ARYLPYRROLIDINYL TRIPEPTIDE HEPATITIS C SERINE PROTEASE INHIBITORS ENANTA PHARMACEUTICALS, INC. 2008-12-25 US disclosed
US-7449447-B2 Peptidomimetic NS3-serine protease inhibitors of hepatitis C virus SCHERING CORPORATION (US) 2008-11-11 US disclosed
US-20080045568-A1 Novel high affinity quinoline-based kinase ligands SCHERING CORPORATION 2008-02-21 US disclosed
US-7084170-B2 Thiophene-amd thiazolesulfonamides as antineoplastic agents ELI LILLY AND COMPANY (US) 2006-08-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080045568-A1 Novel high affinity quinoline-based kinase ligands CDKL2, CDK2, CDKL1 CYP2D6 3846/4885CYP2C9 4575/4885CYP2C19 4055/4885
US-20090005387-A1 QUINOXALINYL MACROCYCLIC HEPATITIS C VIRUS SERINE PROTEASE INHIBITORS PRSS1, SPINT2, CTSC CYP2D6 386/4885CYP2C9 452/4885CYP2C19 444/4885
US-20080317712-A1 ARYLPIPERIDINYL AND ARYLPYRROLIDINYL TRIPEPTIDE HEPATITIS C SERINE PROTEASE INHIBITORS PREP, DNPEP, CTSC CYP2D6 381/4885CYP2C9 312/4885CYP2C19 227/4885
US-20090098085-A1 TETRAZOLYL ACYCLIC HEPATITIS C SERINE PROTEASE INHIBITORS TMPRSS4, PRSS1, SPINT2 CYP2D6 615/4885CYP2C9 300/4885CYP2C19 424/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.