SCHEMBL5655827

SCHEMBL5655827

CCCCOC(=O)C=CC(=O)OCC

nearest known ligand 0.87

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ATM Q13315 1/20 0.87
HCAR2 Q8TDS4 5/20 0.74
MAPT P10636 2/20 0.62
RAB9A P51151 1/20 0.62
NPSR1 Q6W5P4 1/20 0.62
HPGD P15428 1/20 0.61
TSHR P16473 1/20 0.61
ALDH1A1 P00352 2/20 0.52
APP P05067 4/20 0.49
HTT P42858 2/20 0.44
SMN1; SMN2 Q16637 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6661105 1.00 ATM (0.87) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL5655821 1.00 ATM (0.87) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL27619590 0.94 ATM (0.76) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL41998 0.93 ATM (1.00) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL10423863 0.93 ATM (1.00) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL28153 0.93 ATM (1.00) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL269917 0.93 ATM (1.00) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL28154 0.93 ATM (1.00) ATMHCAR2MAPTRAB9ANPSR1
Ethyl Fumarate SCHEMBL11047178 0.92 HCAR2 (0.89) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL11750449 0.92 HCAR2 (0.76) ATMHCAR2MAPTRAB9ANPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12065521-B2 Compound having polycyclic aromatic skeleton, and endoperoxide compound of same KAWASAKI KASEI CHEMICALS LTD. (JP) 2024-08-20 US disclosed
US-20220127385-A1 COMPOUND HAVING POLYCYCLIC AROMATIC SKELETON, AND ENDOPEROXIDE COMPOUND OF SAME KAWASAKI KASEI CHEMICALS LTD. (JP) 2022-04-28 US disclosed
EP-1533322-B1 SOLID CATALYST COMPONENT FOR OLEFIN POLYMERIZATION AND CATALYST TOHO TITANIUM CO LTD (JP) 2019-05-01 EP disclosed
US-9562119-B2 Ethylene polymerization catalysts W. R. GRACE & CO.-CONN. (US) 2017-02-07 US disclosed
EP-2576633-A2 ETHYLENE POLYMERIZATION CATALYSTS BASF Corporation (US) 2013-04-10 EP disclosed
WO-2011149656-A2 ETHYLENE POLYMERIZATION CATALYSTS BASF CORPORATION (US) 2011-12-01 WO disclosed
US-20110294970-A1 ETHYLENE POLYMERIZATION CATALYSTS BASF CATALYSTS, LLC (US) 2011-12-01 US disclosed
US-20060009598-A1 Initiator compositions ARKEMA INC. 2006-01-12 US disclosed
EP-1614698-A1 Initiator compositions Arkema Inc. (US) 2006-01-11 EP disclosed
US-20050227856-A1 Solid catalyst component for olefin polymerization and catalyst TOHO CATALYST CO., LTD. (JP) 2005-10-13 US disclosed
EP-0662641-B1 Resin composition for electrophotographic tone MITSUI CHEMICALS INC (JP) 1999-08-25 EP disclosed
EP-0924537-A1 ANTIREFLECTION ARTICLE DAIKIN INDUSTRIES, LIMITED (JP) 1999-06-23 EP disclosed
US-5468585-A Resin composition for use in an electrophotographic toner MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1995-11-21 US disclosed
EP-0662641-A1 Resin composition for electrophotographic tone MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1995-07-12 EP disclosed
US-4924001-A Process for preparing 5-cyano-4, 5-dihydro-3,4-dicarboxypyrazole derivatives ELI LILLY AND COMPANY (US) 1990-05-08 US disclosed
US-4892956-A 5-cyano-4,5-dihydro-3,4-dicarboxypyrazole derivatives ELI LILLY AND COMPANY (US) 1990-01-09 US disclosed
US-4588776-A OLEFIN-UNSATURATED ACID DIESTER-/METH/ACRYLONITRILE TERPOLYMER MONSANTO COMPANY (US) 1986-05-13 US disclosed
US-4547428-A OLEFIN, DIESTER, SOLUBILIZING MONOMER MONSANTO COMPANY (US) 1985-10-15 US disclosed
EP-0119979-A2 Terpolymers useful as processing aids for vinyl halide polymers Monsanto Company (US) 1984-09-26 EP disclosed
US-4051194-A Thermosetting resin composition for powder paint comprising of a (I) polymer consisting of β-methylglycidyl (meth)acrylate, styrene, unsaturated dialkyl ester, alkylacrylate and (II) saturated aliphatic dibasic acid DAINIPPON INK AND CHEMICALS, INC. (JA) 1977-09-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110294970-A1 ETHYLENE POLYMERIZATION CATALYSTS ESR1, MSMO1, MCM5 ATM 44/4885HCAR2 3524/4885MAPT 1278/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.