Ethyl Fumarate

Ethyl Fumarate

SCHEMBL11047178

CCCCOC(=O)C=CC(=O)OCCCC.CCOC(=O)C=CC(=O)O

nearest known ligand 0.89

Full drug profile on Sugi Atlas →

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 7/20 0.89
ATM Q13315 1/20 0.74
MAPT P10636 2/20 0.56
RAB9A P51151 1/20 0.56
NPSR1 Q6W5P4 1/20 0.56
HPGD P15428 1/20 0.53
TSHR P16473 1/20 0.53
ALDH1A1 P00352 1/20 0.45
APP P05067 1/20 0.44
HTT P42858 2/20 0.40
SMN1; SMN2 Q16637 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Butyl Fumarate SCHEMBL4376900 0.94 HCAR2 (1.00) HCAR2ATMMAPTRAB9ANPSR1
Maleic Acid SCHEMBL28199237 0.94 HCAR2 (1.00) HCAR2ATMMAPTRAB9ANPSR1
Butyl Fumarate SCHEMBL27358297 0.94 HCAR2 (1.00) HCAR2ATMMAPTRAB9ANPSR1
Butyl Fumarate SCHEMBL29604195 0.94 HCAR2 (1.00) HCAR2ATMMAPTRAB9ANPSR1
Butyl Fumarate SCHEMBL43164 0.94 HCAR2 (1.00) HCAR2ATMMAPTRAB9ANPSR1
Butyl Fumarate SCHEMBL124163 0.94 HCAR2 (1.00) HCAR2ATMMAPTRAB9ANPSR1
Butyl Fumarate SCHEMBL43165 0.94 HCAR2 (1.00) HCAR2ATMMAPTRAB9ANPSR1
Maleic Acid SCHEMBL27358295 0.94 HCAR2 (1.00) HCAR2ATMMAPTRAB9ANPSR1
Ethyl Fumarate SCHEMBL9153586 0.93 HCAR2 (0.90) HCAR2ATMMAPTRAB9ANPSR1
Ethyl Fumarate SCHEMBL9153591 0.93 HCAR2 (0.90) HCAR2ATMMAPTRAB9ANPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4431730-A DOPED SILVER HALIDE CORE WITH COVERING SENSITIZED IN PRESENCE OF PPOLYMER FUJI PHOTO FILM CO., LTD. (JP) 1984-02-14 US disclosed